RECRUITING

Factors in Learning And Plasticity: Macular Degeneration

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

A greater understanding of plasticity after central vision loss can inform new therapies for treating low vision and has the potential to benefit millions of individuals suffering from low vision. The treatment of low vision is particularly relevant to the mission of the NEI to support research on visual disorders, mechanisms of visual function, and preservation of sight. The comparison of different training and outcome factors is in line with the NIMH RDOC framework and studies in an aging population are consistent with the mission of the NIA.

Official Title

Characterization of Multiple Factors in Training and Plasticity in Central Vision Loss: Macular Degeneration

Quick Facts

Study Start:2022-11-01
Study Completion:2025-11
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05454124

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 89 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Aged 18-89
  2. * Severely impaired vision in both eyes (20/100 or worse)
  3. * diagnosis of Macular Degeneration by an Ophthalmologist
  4. * Light sensitivity in the macular retina that is at least 10 dB units worse than in peripheral regions, as demonstrated by a scanning laser ophthalmoscope (MAIA)
  5. * Medical record review indicating this level of disease severity has been present for at least 2 years
  6. * Reside within 50 miles of study site
  1. * Pacemaker or any ferromagnetic metal implanted in their body
  2. * Metal of any type implanted in their head (limited dental work is acceptable)
  3. * Claustrophobia
  4. * Being hearing-impaired
  5. * Weight over 300 pounds
  6. * Maximum body girth over 60 inches
  7. * Previous serious head injury
  8. * Presence of hallucinations or delusions
  9. * Excessive old, or colorful tattoos, especially near the head
  10. * Pregnancy
  11. * Braces/permanent retainer

Contacts and Locations

Study Contact

Rachel A Chua, MS
CONTACT
205-410-4041
r2chel@uab.edu
Kristina M Visscher, PhD
CONTACT
205-934-0497
kmv@uab.edu

Study Locations (Sites)

UAB
Birmingham, Alabama, 35294
United States

Collaborators and Investigators

Sponsor: University of Alabama at Birmingham

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-11-01
Study Completion Date2025-11

Study Record Updates

Study Start Date2022-11-01
Study Completion Date2025-11

Terms related to this study

Keywords Provided by Researchers

  • plasticity
  • central vision loss
  • perceptual learning

Additional Relevant MeSH Terms

  • Central Visual Impairment
  • Macular Degeneration