RECRUITING

Sustained Release Oral Formulation for Treatment of Parkinson's Disease

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Achieving sustained blood levels of carbidopa/levodopa has been a challenge in the treatment of PD and although levodopa remains the most commonly used drug, motor fluctuations remain a major disability especially in advanced Parkinson's disease. The aim of this study is to determine the efficacy of a novel oral carbidopa-levodopa formulation in achieving a sustained blood level of levodopa and carbidopa in normal volunteers.

Official Title

Sustained Release Oral Formulation for Treatment of Parkinson's Disease

Quick Facts

Study Start:2025-06-12
Study Completion:2026-06-16
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05471609

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Normal healthy
  2. * Are 18-65 years of age
  3. * Are not currently taking medications regularly
  4. * Able to fast 6 hours (water allowed)
  1. * Pregnancy
  2. * Inability to fast

Contacts and Locations

Study Contact

Clinical Research, RN
CONTACT
612-625-2350
umnstudies@gmail.com

Principal Investigator

Khalaf Bushara, MD,FRCP
PRINCIPAL_INVESTIGATOR
University of Minnesota

Study Locations (Sites)

University of Minnesota
Minneapolis, Minnesota, 55455
United States

Collaborators and Investigators

Sponsor: University of Minnesota

  • Khalaf Bushara, MD,FRCP, PRINCIPAL_INVESTIGATOR, University of Minnesota

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-06-12
Study Completion Date2026-06-16

Study Record Updates

Study Start Date2025-06-12
Study Completion Date2026-06-16

Terms related to this study

Keywords Provided by Researchers

  • Idiopathic Parkinson Disease
  • levodopa/carbidopa

Additional Relevant MeSH Terms

  • Idiopathic Parkinson Disease