RECRUITING

Sustained Release Oral Formulation for Treatment of Parkinson's Disease

Description

Achieving sustained blood levels of carbidopa/levodopa has been a challenge in the treatment of PD and although levodopa remains the most commonly used drug, motor fluctuations remain a major disability especially in advanced Parkinson's disease. The aim of this study is to determine the efficacy of a novel oral carbidopa-levodopa formulation in achieving a sustained blood level of levodopa and carbidopa in normal volunteers.

Study Overview

Study Details

Study overview

Achieving sustained blood levels of carbidopa/levodopa has been a challenge in the treatment of PD and although levodopa remains the most commonly used drug, motor fluctuations remain a major disability especially in advanced Parkinson's disease. The aim of this study is to determine the efficacy of a novel oral carbidopa-levodopa formulation in achieving a sustained blood level of levodopa and carbidopa in normal volunteers.

Sustained Release Oral Formulation for Treatment of Parkinson's Disease

Sustained Release Oral Formulation for Treatment of Parkinson's Disease

Condition
Idiopathic Parkinson Disease
Intervention / Treatment

-

Contacts and Locations

Minneapolis

University of Minnesota, Minneapolis, Minnesota, United States, 55455

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Normal healthy
  • * Are 18-65 years of age
  • * Are not currently taking medications regularly
  • * Able to fast 6 hours (water allowed)
  • * Pregnancy
  • * Inability to fast

Ages Eligible for Study

18 Years to 65 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Minnesota,

Khalaf Bushara, MD,FRCP, PRINCIPAL_INVESTIGATOR, University of Minnesota

Study Record Dates

2026-06-16