RECRUITING

Overcoming Nicotine Dependence to Enable Quitting

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Tobacco use disorder is a chronic, relapsing health condition that necessitates a chronic care approach. However, traditional smoking cessation treatment programs allocate nearly all their resources only to those smokers who are willing to set a quit date. This is problematic because few smokers are ready to set a quit date at any given time, and a smoker's stated intention to quit can change rapidly. One novel potential treatment strategy is to foster practice quitting (PQ), defined as attempting to not smoke for a few hours or days, without pressure or expectation to permanently quit. Although a growing body of evidence supports the role of practice quitting in fostering permanent quit attempts and cessation, there is a significant knowledge gap regarding which treatment strategies should be used to engage smokers in practice quitting. The proposed study will test the role of PQ counseling vs. Motivational Interviewing (MI) counseling, and NRT sampling (four-week supply of nicotine lozenges and patches) vs. none.

Official Title

A Mechanistic Test of Treatment Strategies to Foster Practice Quitting

Quick Facts

Study Start:2023-03-24
Study Completion:2027-08-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05513872

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. are 18 years or older
  2. 2. report current daily cigarette smoking (≥ 5 cigarettes per day)
  3. 3. are not planning to quit in the next 30 days
  4. 4. are not currently engaged in smoking cessation treatment
  5. 5. are motivated to quit or engage in a non-cessation goal (i.e., reduce smoking, learn more about treatment options, and/ or try out skills to change smoking) in the next 6 months
  6. 6. are English speaking
  7. 7. reside in the continental United States
  8. 8. have access to a smartphone that can be used to complete study procedures
  1. 1. are pregnant/breastfeeding
  2. 2. had recent cardiovascular trauma such as myocardial infarction
  3. 3. had a stroke within the past 3 months

Contacts and Locations

Study Contact

Maritza Esqueda-Medina
CONTACT
312-563-3702
on-deq@rush.edu
Amanda Mathew
CONTACT
312-563-1273
on-deq@rush.edu

Principal Investigator

Amanda Mathew, PhD
PRINCIPAL_INVESTIGATOR
Rush University Medical Center

Study Locations (Sites)

Rush University Medical Center
Chicago, Illinois, 60612
United States

Collaborators and Investigators

Sponsor: Rush University Medical Center

  • Amanda Mathew, PhD, PRINCIPAL_INVESTIGATOR, Rush University Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-03-24
Study Completion Date2027-08-30

Study Record Updates

Study Start Date2023-03-24
Study Completion Date2027-08-30

Terms related to this study

Keywords Provided by Researchers

  • tobacco
  • smoking cessation
  • nicotine dependence
  • nicotine replacement therapy
  • behavioral treatment

Additional Relevant MeSH Terms

  • Tobacco Use
  • Smoking Cessation
  • Smoking Behaviors
  • Nicotine Dependence
  • Nicotine Withdrawal