RECRUITING

Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The primary objective of this study is to develop and train the Elephas live tumor diagnostic platform and determine the ex-vivo accuracy of the Elephas Score using in-vivo RECIST 1.1 as the reference method

Official Title

Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform (ELEPHAS-02)

Quick Facts

Study Start:2023-06-26
Study Completion:2027-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05520099

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Catarina Costa
CONTACT
(609) 955 4927
ClinicalTrials@elephas.com

Principal Investigator

Fred Hausheer, MD, FACP
STUDY_DIRECTOR
Elephas

Study Locations (Sites)

CARTI Cancer Center
Little Rock, Arkansas, 72205
United States
Salinas Valley Memorial Healthcare System
Salinas, California, 93901
United States
AdventHealth Orlando
Orlando, Florida, 32803
United States
Memorial Health System
Pembroke Pines, Florida, 33026
United States
Cleveland Clinic Florida
Stuart, Florida, 34994
United States
University of South Florida (Tampa General Hospital)
Tampa, Florida, 33606
United States
University of Louisville James Graham Brown Cancer Center
Louisville, Kentucky, 40202
United States
Meritus Center for Clinical Research
Hagerstown, Maryland, 21742
United States
John Theurer Cancer Center
Hackensack, New Jersey, 07601
United States
Roswell Park Comprehensive Cancer Center
Buffalo, New York, 14203
United States
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, 27599
United States
University of Wisconsin
Madison, Wisconsin, 53705
United States

Collaborators and Investigators

Sponsor: Elephas

  • Fred Hausheer, MD, FACP, STUDY_DIRECTOR, Elephas

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-06-26
Study Completion Date2027-01

Study Record Updates

Study Start Date2023-06-26
Study Completion Date2027-01

Terms related to this study

Keywords Provided by Researchers

  • Immunotherapy
  • Live Tumor Fragment
  • Elephas
  • Elephas Score
  • Core Needle Biopsy
  • Forceps Biopsy
  • Punch Biopsy
  • Immune Checkpoint Inhibitors
  • Ex vivo Platform

Additional Relevant MeSH Terms

  • Immunotherapy
  • Cancer
  • Bladder Cancer
  • Urothelial Carcinoma Bladder
  • Kidney Cancer
  • Clear Cell Renal Cell Cancer (ccRCC)
  • Colorectal Cancer
  • MSI-H Colorectal Cancer
  • DMMR Colorectal Cancer
  • Head and Neck Cancer (H&N)
  • Squamous Cell Carcinoma Head and Neck Cancer (HNSCC)
  • Liver Cancer
  • Hepatocellular Carcinoma (HCC)
  • Lung Cancer (NSCLC)
  • NSCLC (Non-small Cell Lung Cancer)
  • Skin Cancer
  • Cutaneous Melanoma
  • Endometrial Cancer
  • Solid Tumor Cancer