RECRUITING

Applying pGz in Mitochondrial Disease

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This is a multi-aim study, studying the effects of conventional exercise (measured through Cardiopulomary Exercises Testing or an in-bed pedal exercise) and passive exercise through periodic acceleration (pGz). Aim 1 will focus on the differences between primary mitochondrial disease (PMD) patients and healthy volunteers. Aim 2 is an exploratory aim, which will be studying the effects in patients admitted to the Children's Hospital of Philadelphia Pediatric Intensive Care Unit (PICU).

Official Title

The Utility of pGz in Primary Mitochondrial Disorders

Quick Facts

Study Start:2023-03-22
Study Completion:2024-10
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05569122

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:10 Years to 60 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD, ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Katelynn Stanley, BS
CONTACT
215-426-0225
stanleyk2@chop.edu
Daniel McGinn, MSGC
CONTACT
215-590-1000
mcginnde@chop.edu

Principal Investigator

Zuela Zolkipli-Cunningham, MBChB, MRCP
PRINCIPAL_INVESTIGATOR
Attending Physician

Study Locations (Sites)

Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104
United States

Collaborators and Investigators

Sponsor: Children's Hospital of Philadelphia

  • Zuela Zolkipli-Cunningham, MBChB, MRCP, PRINCIPAL_INVESTIGATOR, Attending Physician

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-03-22
Study Completion Date2024-10

Study Record Updates

Study Start Date2023-03-22
Study Completion Date2024-10

Terms related to this study

Keywords Provided by Researchers

  • Passive Exercise
  • periodic acceleration

Additional Relevant MeSH Terms

  • Mitochondrial Myopathies
  • Mitochondrial Diseases