RECRUITING

Evaluation of 18F-TFB PET/CT Scan in Patients With Differentiated Thyroid Cancer

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This phase II study evaluates F-18 tetrafluoroborate (18F-TFB) PET/CT scan in patients with differentiated thyroid cancer. Diagnostic imaging is necessary for planning treatment, monitoring therapy response, and identifying sites of recurrent or metastatic disease in differentiated thyroid cancer. 18F-TFB PET/CT may accurately detect recurrent and metastatic thyroid cancer lesions, with the potential to provide information for patient management that is better than the current standard of care imaging practices.

Official Title

Evaluation of F-18 Tetrafluoroborate (18F-TFB) PET/CT in Patients With Differentiated Thyroid Cancer

Quick Facts

Study Start:2022-04-22
Study Completion:2026-05-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05575440

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Subject has biopsy-proven papillary or follicular thyroid cancer
  2. * Subject is clinically indicated for 123I-SPECT/CT total body iodine (TBI) scan
  3. * Subject agrees to undergo 18F-TFB PET/CT scan following TBI scan
  4. * Karnofsky performance status of \>= 50 (or Eastern Cooperative Oncology Group \[ECOG\]/World Health Organization \[WHO\] equivalent)
  5. * Subject is able to be scanned - able to lie still on SPECT/CT and PET/CT scanner table for up to 65 minutes (min)
  6. * Age 18 or older
  7. * Ability to understand a written informed consent document, and the willingness to sign it
  8. * Subject is not pregnant
  1. * Contrast-enhanced CT within 4 last weeks
  2. * Amiodarone within last 4 months
  3. * Ingested iodine, kelp tablets, Lugols iodine, or potassium iodide (SSKI) within 2 weeks
  4. * Unable to lie flat, still or tolerate a PET scan
  5. * Applied betadine, iodoform, or quick tanning products to skin within last two weeks
  6. * If using medication withdrawal for stimulation, then exclude if thyroid stimulating hormone (TSH) level \< 25
  7. * Taken anti-thyroid medication within 1 week
  8. * Subject is breastfeeding
  9. * Positive pregnancy test

Contacts and Locations

Principal Investigator

Stephen M. Broski, M.D.
PRINCIPAL_INVESTIGATOR
Mayo Clinic in Rochester

Study Locations (Sites)

Mayo Clinic in Rochester
Rochester, Minnesota, 55905
United States

Collaborators and Investigators

Sponsor: Mayo Clinic

  • Stephen M. Broski, M.D., PRINCIPAL_INVESTIGATOR, Mayo Clinic in Rochester

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-04-22
Study Completion Date2026-05-01

Study Record Updates

Study Start Date2022-04-22
Study Completion Date2026-05-01

Terms related to this study

Additional Relevant MeSH Terms

  • Differentiated Thyroid Gland Carcinoma
  • Thyroid Gland Follicular Carcinoma
  • Thyroid Gland Papillary Carcinoma