ACTIVE_NOT_RECRUITING

Testing the Addition of an Anti-Cancer Drug, Irinotecan, to the Standard Chemotherapy Treatment (FOLFOX) After Long-Course Radiation Therapy for Advanced-Stage Rectal Cancers to Improve the Rate of Complete Response and Long-Term Rates of Organ Preservation

Talk to us

Conditions

Locally Advanced Rectal CarcinomaStage II Rectal Cancer AJCC v8Stage III Rectal Cancer AJCC v8

Quick Navigation

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This phase II trial compares the effect of irinotecan versus oxaliplatin after long-course chemoradiation in patients with stage II-III rectal cancer. Combination chemotherapy drugs, such as FOLFIRINOX (fluorouracil, irinotecan, leucovorin, and oxaliplatin), FOLFOX (leucovorin, fluorouracil, oxaliplatin, and irinotecan ), and CAPOX (capecitabin and oxaliplatin) work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. FOLFOX or CAPOX are used after chemoradiation as usual treatment for rectal cancer. Giving FOLFIRINOX after chemoradiation may increase the response rate and lead to higher rates of clinical complete response (with a chance of avoiding surgery) compared to FOLFOX or CAPOX after chemoradiation in patients with locally advanced rectal cancer.

Official Title

The Janus Rectal Cancer Trial: A Randomized Phase II Trial Testing The Efficacy of Triplet Versus Doublet Chemotherapy to Achieve Clinical Complete Response in Patients With Locally Advanced Rectal Cancer

Quick Facts

Study Start:2022-12-08
Study Completion:2032-09-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:ACTIVE_NOT_RECRUITING

Study ID

NCT05610163

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Stage: Clinical stage II or III rectal adenocarcinoma defined as T4N0 or any T with node positive disease (any T, N+); also T3N0 requiring abdominal perineal resection (APR) or coloanal anastomosis
  2. * Tumor site: Rectum; =\< 12cm from the anal verge
  3. * No prior systemic chemotherapy, targeted therapy, or immunotherapy; or radiation therapy administered as treatment for colorectal cancer within the past 5 years is allowed
  4. * Not pregnant and not nursing, because this study involves an agent that has known genotoxic, mutagenic and teratogenic effects
  5. * Age \>= 18 years
  6. * Eastern Cooperative Oncology Group (ECOG) performance status =\< 2 (or Karnofsky \>= 60%)
  7. * Absolute neutrophil count (ANC) \>= 1,500/mm\^3
  8. * Platelet count \>= 100,000/mm
  9. * Creatinine =\< 1.5 x upper limit of normal (ULN) OR calculated (calc.) creatinine clearance \>= 50 mL/min
  10. * Total bilirubin =\< 1.5 x upper limit of normal (ULN)
  11. * Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) =\< 3 x upper limit of normal (ULN)
  12. * No upper rectal tumors (distal margin of tumor \> 12 cm from the anal verge)
  13. * No recurrent rectal cancer; prior transanal excision, prior distal sigmoid cancer with a low anastomosis
  14. * No known mismatch repair deficient rectal adenocarcinoma
  15. * Human immunodeficiency virus HIV-infected patients on effective anti-retro viral therapy with undetectable viral load within 6 months are eligible for this trial
  16. * Patients with known history or current symptoms of cardiac disease, or history of treatment with cardio toxic agents, should have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification1. To be eligible for this trial, patients should be class 2B or better
  17. * Chronic concomitant treatment with strong inhibitors of CYP3A4 is not allowed on this study. Patients on strong CYP3A4 inhibitors must discontinue the drug for 14 days prior to registration on the study \* Chronic concomitant treatment with strong CYP3A4 inducers is not allowed. Patients must discontinue the drug 14 days prior to the start of study treatment
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Principal Investigator

J. Joshua Smith, MD
STUDY_CHAIR
Memorial Sloan Kettering Cancer Center

Study Locations (Sites)

University of Alabama at Birmingham Cancer Center
Birmingham, Alabama, 35233
United States
University of South Alabama Mitchell Cancer Institute
Mobile, Alabama, 36688
United States
Anchorage Associates in Radiation Medicine
Anchorage, Alaska, 98508
United States
Alaska Breast Care and Surgery LLC
Anchorage, Alaska, 99508
United States
Alaska Oncology and Hematology LLC
Anchorage, Alaska, 99508
United States
Alaska Women's Cancer Care
Anchorage, Alaska, 99508
United States
Anchorage Oncology Centre
Anchorage, Alaska, 99508
United States
Katmai Oncology Group
Anchorage, Alaska, 99508
United States
Providence Alaska Medical Center
Anchorage, Alaska, 99508
United States
Kingman Regional Medical Center
Kingman, Arizona, 86401
United States
Cancer Center at Saint Joseph's
Phoenix, Arizona, 85004
United States
Mayo Clinic Hospital in Arizona
Phoenix, Arizona, 85054
United States
Mercy Hospital Fort Smith
Fort Smith, Arkansas, 72903
United States
NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro
Jonesboro, Arkansas, 72401
United States
University of Arkansas for Medical Sciences
Little Rock, Arkansas, 72205
United States
Mission Hope Medical Oncology - Arroyo Grande
Arroyo Grande, California, 93420
United States
PCR Oncology
Arroyo Grande, California, 93420
United States
Keck Medicine of USC Buena Park
Buena Park, California, 90621
United States
Providence Saint Joseph Medical Center/Disney Family Cancer Center
Burbank, California, 91505
United States
Mercy Cancer Center - Carmichael
Carmichael, California, 95608
United States
Mercy San Juan Medical Center
Carmichael, California, 95608
United States
City of Hope Comprehensive Cancer Center
Duarte, California, 91010
United States
Mercy Cancer Center - Elk Grove
Elk Grove, California, 95758
United States
Washington Hospital
Fremont, California, 94538
United States
UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care
Irvine, California, 92612
United States
City of Hope at Irvine Lennar
Irvine, California, 92618
United States
Los Angeles General Medical Center
Los Angeles, California, 90033
United States
USC / Norris Comprehensive Cancer Center
Los Angeles, California, 90033
United States
Mercy Cancer Center
Merced, California, 95340
United States
Providence Queen of The Valley
Napa, California, 94558
United States
USC Norris Oncology/Hematology-Newport Beach
Newport Beach, California, 92663
United States
Saint Joseph Hospital - Orange
Orange, California, 92868
United States
UC Irvine Health/Chao Family Comprehensive Cancer Center
Orange, California, 92868
United States
Mercy Cancer Center - Rocklin
Rocklin, California, 95765
United States
Mercy Cancer Center - Sacramento
Sacramento, California, 95816
United States
University of California Davis Comprehensive Cancer Center
Sacramento, California, 95817
United States
Salinas Valley Memorial
Salinas, California, 93901
United States
Pacific Central Coast Health Center-San Luis Obispo
San Luis Obispo, California, 93401
United States
Mission Hope Medical Oncology - Santa Maria
Santa Maria, California, 93444
United States
Providence Medical Foundation - Santa Rosa
Santa Rosa, California, 95403
United States
City of Hope South Pasadena
South Pasadena, California, 91030
United States
Saint Helena Hospital
St. Helena, California, 94574
United States
Saint Joseph's Medical Center
Stockton, California, 95204
United States
City of Hope South Bay
Torrance, California, 90503
United States
Gene Upshaw Memorial Tahoe Forest Cancer Center
Truckee, California, 96161
United States
City of Hope Upland
Upland, California, 91786
United States
John Muir Medical Center-Walnut Creek
Walnut Creek, California, 94598
United States
Woodland Memorial Hospital
Woodland, California, 95695
United States
UCHealth University of Colorado Hospital
Aurora, Colorado, 80045
United States
Penrose-Saint Francis Healthcare
Colorado Springs, Colorado, 80907
United States
Rocky Mountain Cancer Centers-Penrose
Colorado Springs, Colorado, 80907
United States
UCHealth Memorial Hospital Central
Colorado Springs, Colorado, 80909
United States
Memorial Hospital North
Colorado Springs, Colorado, 80920
United States
Saint Francis Cancer Center
Colorado Springs, Colorado, 80923
United States
UCHealth - Cherry Creek
Denver, Colorado, 80206
United States
AdventHealth Porter
Denver, Colorado, 80210
United States
Saint Joseph Hospital - Cancer Centers of Colorado
Denver, Colorado, 80218
United States
Lutheran Hospital - Cancer Centers of Colorado
Golden, Colorado, 80401
United States
Saint Mary's Hospital and Regional Medical Center
Grand Junction, Colorado, 81501
United States
UCHealth Highlands Ranch Hospital
Highlands Ranch, Colorado, 80129
United States
Saint Anthony Hospital
Lakewood, Colorado, 80228
United States
AdventHealth Littleton
Littleton, Colorado, 80122
United States
Longmont United Hospital
Longmont, Colorado, 80501
United States
AdventHealth Parker
Parker, Colorado, 80138
United States
Saint Mary Corwin Medical Center
Pueblo, Colorado, 81004
United States
Saint Anthony North Hospital
Westminster, Colorado, 80023
United States
Intermountain Health Lutheran Hospital
Wheat Ridge, Colorado, 80401
United States
Hartford Hospital
Hartford, Connecticut, 06102
United States
Midstate Medical Center
Meriden, Connecticut, 06451
United States
The Hospital of Central Connecticut
New Britain, Connecticut, 06050
United States
Beebe Medical Center
Lewes, Delaware, 19958
United States
Beebe South Coastal Health Campus
Millville, Delaware, 19967
United States
Delaware Clinical and Laboratory Physicians PA
Newark, Delaware, 19713
United States
Helen F Graham Cancer Center
Newark, Delaware, 19713
United States
Medical Oncology Hematology Consultants PA
Newark, Delaware, 19713
United States
Christiana Care Health System-Christiana Hospital
Newark, Delaware, 19718
United States
Beebe Health Campus
Rehoboth Beach, Delaware, 19971
United States
Christiana Care Health System-Wilmington Hospital
Wilmington, Delaware, 19801
United States
MedStar Georgetown University Hospital
Washington D.C., District of Columbia, 20007
United States
MedStar Washington Hospital Center
Washington D.C., District of Columbia, 20010
United States
George Washington University Medical Center
Washington D.C., District of Columbia, 20037
United States
AdventHealth Altamonte
Altamonte Springs, Florida, 32701
United States
Mount Sinai Comprehensive Cancer Center at Aventura
Aventura, Florida, 33180
United States
AdventHealth Celebration
Celebration, Florida, 34747
United States
Morton Plant Hospital
Clearwater, Florida, 33756
United States
Holy Cross Hospital
Fort Lauderdale, Florida, 33308
United States
University of Florida Health Science Center - Gainesville
Gainesville, Florida, 32610
United States
Memorial Regional Hospital/Joe DiMaggio Children's Hospital
Hollywood, Florida, 33021
United States
Mayo Clinic in Florida
Jacksonville, Florida, 32224-9980
United States
AdventHealth Kissimmee
Kissimmee, Florida, 34744
United States
Saint Joseph's Hospital-North
Lutz, Florida, 33558
United States
Mount Sinai Medical Center
Miami Beach, Florida, 33140
United States
AdventHealth Orlando
Orlando, Florida, 32803
United States
AdventHealth East Orlando
Orlando, Florida, 32822
United States
Memorial Hospital West
Pembroke Pines, Florida, 33028
United States
Saint Anthony's Hospital Cancer Care Center
St. Petersburg, Florida, 33705
United States
Tampa General Hospital
Tampa, Florida, 33606
United States
Saint Joseph's Hospital/Children's Hospital-Tampa
Tampa, Florida, 33607
United States
Emory University Hospital Midtown
Atlanta, Georgia, 30308
United States
Emory University Hospital/Winship Cancer Institute
Atlanta, Georgia, 30322
United States
Emory Saint Joseph's Hospital
Atlanta, Georgia, 30342
United States
Emory Decatur Hospital
Decatur, Georgia, 30033
United States
Emory Johns Creek Hospital
Johns Creek, Georgia, 30097
United States
Memorial Health University Medical Center
Savannah, Georgia, 31404
United States
Hawaii Cancer Care Inc - Waterfront Plaza
Honolulu, Hawaii, 96813
United States
Queen's Cancer Cenrer - POB I
Honolulu, Hawaii, 96813
United States
Queen's Medical Center
Honolulu, Hawaii, 96813
United States
Straub Clinic and Hospital
Honolulu, Hawaii, 96813
United States
University of Hawaii Cancer Center
Honolulu, Hawaii, 96813
United States
Kuakini Medical Center
Honolulu, Hawaii, 96817
United States
Queen's Cancer Center - Kuakini
Honolulu, Hawaii, 96817
United States
The Cancer Center of Hawaii-Liliha
Honolulu, Hawaii, 96817
United States
Kapiolani Medical Center for Women and Children
Honolulu, Hawaii, 96826
United States
Castle Medical Center
Kailua, Hawaii, 96734
United States
Wilcox Memorial Hospital and Kauai Medical Clinic
Lihue, Hawaii, 96766
United States
Hawaii Cancer Care - Westridge
‘Aiea, Hawaii, 96701
United States
Pali Momi Medical Center
‘Aiea, Hawaii, 96701
United States
Queen's Cancer Center - Pearlridge
‘Aiea, Hawaii, 96701
United States
The Cancer Center of Hawaii-Pali Momi
‘Aiea, Hawaii, 96701
United States
The Queen's Medical Center - West Oahu
‘Ewa Beach, Hawaii, 96706
United States
Saint Alphonsus Cancer Care Center-Boise
Boise, Idaho, 83706
United States
Saint Luke's Cancer Institute - Boise
Boise, Idaho, 83712
United States
Saint Alphonsus Cancer Care Center-Caldwell
Caldwell, Idaho, 83605
United States
Kootenai Health - Coeur d'Alene
Coeur d'Alene, Idaho, 83814
United States
Saint Luke's Cancer Institute - Fruitland
Fruitland, Idaho, 83619
United States
Idaho Urologic Institute-Meridian
Meridian, Idaho, 83642
United States
Saint Luke's Cancer Institute - Meridian
Meridian, Idaho, 83642
United States
Saint Alphonsus Cancer Care Center-Nampa
Nampa, Idaho, 83687
United States
Saint Luke's Cancer Institute - Nampa
Nampa, Idaho, 83687
United States
Kootenai Clinic Cancer Services - Post Falls
Post Falls, Idaho, 83854
United States
Saint Luke's Cancer Institute - Twin Falls
Twin Falls, Idaho, 83301
United States
OSF Saint Anthony's Health Center
Alton, Illinois, 62002
United States
Rush-Copley Medical Center
Aurora, Illinois, 60504
United States
Advocate Outpatient Center - Aurora
Aurora, Illinois, 60506
United States
Advocate Good Shepherd Hospital
Barrington, Illinois, 60010
United States
OSF Saint Joseph Medical Center
Bloomington, Illinois, 61701
United States
Illinois CancerCare-Bloomington
Bloomington, Illinois, 61704
United States
Illinois CancerCare-Canton
Canton, Illinois, 61520
United States
Memorial Hospital of Carbondale
Carbondale, Illinois, 62902
United States
SIH Cancer Institute
Carterville, Illinois, 62918
United States
Illinois CancerCare-Carthage
Carthage, Illinois, 62321
United States
Centralia Oncology Clinic
Centralia, Illinois, 62801
United States
Saint Mary's Hospital
Centralia, Illinois, 62801
United States
Northwestern University
Chicago, Illinois, 60611
United States
John H Stroger Jr Hospital of Cook County
Chicago, Illinois, 60612
United States
University of Chicago Comprehensive Cancer Center
Chicago, Illinois, 60637
United States
Advocate Illinois Masonic Medical Center
Chicago, Illinois, 60657
United States
AMG Crystal Lake - Oncology
Crystal Lake, Illinois, 60014
United States
Carle at The Riverfront
Danville, Illinois, 61832
United States
Cancer Care Specialists of Illinois - Decatur
Decatur, Illinois, 62526
United States
Decatur Memorial Hospital
Decatur, Illinois, 62526
United States
Northwestern Medicine Cancer Center Kishwaukee
DeKalb, Illinois, 60115
United States
Illinois CancerCare-Dixon
Dixon, Illinois, 61021
United States
Advocate Good Samaritan Hospital
Downers Grove, Illinois, 60515
United States
Carle Physician Group-Effingham
Effingham, Illinois, 62401
United States
Crossroads Cancer Center
Effingham, Illinois, 62401
United States
Advocate Sherman Hospital
Elgin, Illinois, 60123
United States
Elmhurst Memorial Hospital
Elmhurst, Illinois, 60126
United States
Illinois CancerCare-Eureka
Eureka, Illinois, 61530
United States
Illinois CancerCare-Galesburg
Galesburg, Illinois, 61401
United States
Western Illinois Cancer Treatment Center
Galesburg, Illinois, 61401
United States
Northwestern Medicine Cancer Center Delnor
Geneva, Illinois, 60134
United States
Northwestern Medicine Glenview Outpatient Center
Glenview, Illinois, 60026
United States
Northwestern Medicine Grayslake Outpatient Center
Grayslake, Illinois, 60030
United States
Ingalls Memorial Hospital
Harvey, Illinois, 60426
United States
Advocate South Suburban Hospital
Hazel Crest, Illinois, 60429
United States
Illinois CancerCare-Kewanee Clinic
Kewanee, Illinois, 61443
United States
Northwestern Medicine Lake Forest Hospital
Lake Forest, Illinois, 60045
United States
AMG Libertyville - Oncology
Libertyville, Illinois, 60048
United States
Condell Memorial Hospital
Libertyville, Illinois, 60048
United States
Illinois CancerCare-Macomb
Macomb, Illinois, 61455
United States
Carle Physician Group-Mattoon/Charleston
Mattoon, Illinois, 61938
United States
SSM Health Good Samaritan
Mount Vernon, Illinois, 62864
United States
Edward Hospital/Cancer Center
Naperville, Illinois, 60540
United States
UC Comprehensive Cancer Center at Silver Cross
New Lenox, Illinois, 60451
United States
Carle BroMenn Medical Center
Normal, Illinois, 61761
United States
Carle Cancer Institute Normal
Normal, Illinois, 61761
United States
Cancer Care Center of O'Fallon
O'Fallon, Illinois, 62269
United States
HSHS Saint Elizabeth's Hospital
O'Fallon, Illinois, 62269
United States
Advocate Christ Medical Center
Oak Lawn, Illinois, 60453-2699
United States
University of Chicago Medicine-Orland Park
Orland Park, Illinois, 60462
United States
Illinois CancerCare-Ottawa Clinic
Ottawa, Illinois, 61350
United States
Advocate High Tech Medical Park
Palos Heights, Illinois, 60463
United States
Advocate Lutheran General Hospital
Park Ridge, Illinois, 60068
United States
Illinois CancerCare-Pekin
Pekin, Illinois, 61554
United States
Illinois CancerCare-Peoria
Peoria, Illinois, 61615
United States
Methodist Medical Center of Illinois
Peoria, Illinois, 61636
United States
Illinois CancerCare-Peru
Peru, Illinois, 61354
United States
Valley Radiation Oncology
Peru, Illinois, 61354
United States
Edward Hospital/Cancer Center?Plainfield
Plainfield, Illinois, 60585
United States
Illinois CancerCare-Princeton
Princeton, Illinois, 61356
United States
Southern Illinois University School of Medicine
Springfield, Illinois, 62702
United States
Springfield Clinic
Springfield, Illinois, 62702
United States
Springfield Memorial Hospital
Springfield, Illinois, 62781
United States
Carle Cancer Center
Urbana, Illinois, 61801
United States
Northwestern Medicine Cancer Center Warrenville
Warrenville, Illinois, 60555
United States
Illinois CancerCare - Washington
Washington, Illinois, 61571
United States
Northwest Cancer Center - Main Campus
Crown Point, Indiana, 46307
United States
Northwest Oncology LLC
Dyer, Indiana, 46311
United States
Parkview Regional Medical Center
Fort Wayne, Indiana, 46845
United States
Northwest Cancer Center - Hobart
Hobart, Indiana, 46342
United States
Saint Mary Medical Center
Hobart, Indiana, 46342
United States
The Community Hospital
Munster, Indiana, 46321
United States
Women's Diagnostic Center - Munster
Munster, Indiana, 46321
United States
Baptist Health Floyd
New Albany, Indiana, 47150
United States
Reid Health
Richmond, Indiana, 47374
United States
Northwest Cancer Center - Valparaiso
Valparaiso, Indiana, 46383
United States
UI Health Care Mission Cancer and Blood - Ankeny Clinic
Ankeny, Iowa, 50023
United States
Mercy Hospital
Cedar Rapids, Iowa, 52403
United States
Oncology Associates at Mercy Medical Center
Cedar Rapids, Iowa, 52403
United States
Mercy Cancer Center-West Lakes
Clive, Iowa, 50325
United States
UI Health Care Mission Cancer and Blood - West Des Moines Clinic
Clive, Iowa, 50325
United States
Greater Regional Medical Center
Creston, Iowa, 50801
United States
Iowa Methodist Medical Center
Des Moines, Iowa, 50309
United States
UI Health Care Mission Cancer and Blood - Des Moines Clinic
Des Moines, Iowa, 50309
United States
Mercy Medical Center - Des Moines
Des Moines, Iowa, 50314
United States
UI Health Care Mission Cancer and Blood - Laurel Clinic
Des Moines, Iowa, 50314
United States
UI Health Care Mission Cancer and Blood - Waukee Clinic
Waukee, Iowa, 50263
United States
Mercy Medical Center-West Lakes
West Des Moines, Iowa, 50266
United States
Central Care Cancer Center - Garden City
Garden City, Kansas, 67846
United States
Central Care Cancer Center - Great Bend
Great Bend, Kansas, 67530
United States
Baptist Health Corbin
Corbin, Kentucky, 40701
United States
Saint Elizabeth Healthcare Edgewood
Edgewood, Kentucky, 41017
United States
Saint Elizabeth Healthcare Fort Thomas
Fort Thomas, Kentucky, 41075
United States
Baptist Health Lexington
Lexington, Kentucky, 40503
United States
Saint Joseph Hospital
Lexington, Kentucky, 40504
United States
Saint Joseph Radiation Oncology Resource Center
Lexington, Kentucky, 40504
United States
Baptist Health Hamburg
Lexington, Kentucky, 40509
United States
Saint Joseph Hospital East
Lexington, Kentucky, 40509
United States
University of Kentucky/Markey Cancer Center
Lexington, Kentucky, 40536
United States
The James Graham Brown Cancer Center at University of Louisville
Louisville, Kentucky, 40202
United States
Baptist Health Louisville
Louisville, Kentucky, 40207
United States
UofL Health Medical Center Northeast
Louisville, Kentucky, 40245
United States
Baptist Health Paducah
Paducah, Kentucky, 42003
United States
Ochsner Hematology Oncology North Shore - Covington (West Region)
Covington, Louisiana, 70433
United States
University Medical Center New Orleans
New Orleans, Louisiana, 70112
United States
Ochsner Medical Center Jefferson
New Orleans, Louisiana, 70121
United States
Lafayette Family Cancer Center-EMMC
Brewer, Maine, 04412
United States
Sinai Hospital of Baltimore
Baltimore, Maryland, 21215
United States
MedStar Franklin Square Medical Center/Weinberg Cancer Institute
Baltimore, Maryland, 21237
United States
MedStar Good Samaritan Hospital
Baltimore, Maryland, 21239
United States
UPMC Western Maryland
Cumberland, Maryland, 21502
United States
William E Kahlert Regional Cancer Center/Sinai Hospital
Westminster, Maryland, 21157
United States
Boston Medical Center
Boston, Massachusetts, 02118
United States
Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215
United States
Dana-Farber Cancer Institute
Boston, Massachusetts, 02215
United States
Lahey Hospital and Medical Center
Burlington, Massachusetts, 01805
United States
Dana-Farber Cancer Institute at Foxborough
Foxborough, Massachusetts, 02035
United States
Dana Farber-Merrimack Valley
Methuen, Massachusetts, 01844
United States
Dana-Farber/Brigham and Women's Cancer Center at Milford Regional
Milford, Massachusetts, 01757
United States
Lahey Medical Center-Peabody
Peabody, Massachusetts, 01960
United States
Dana-Farber/Brigham and Women's Cancer Center at South Shore
South Weymouth, Massachusetts, 02190
United States
Trinity Health Saint Joseph Mercy Hospital Ann Arbor
Ann Arbor, Michigan, 48106
United States
University of Michigan Comprehensive Cancer Center
Ann Arbor, Michigan, 48109
United States
Trinity Health IHA Medical Group Hematology Oncology - Brighton
Brighton, Michigan, 48114
United States
Trinity Health Medical Center - Brighton
Brighton, Michigan, 48114
United States
University of Michigan - Brighton Center for Specialty Care
Brighton, Michigan, 48116
United States
Henry Ford Cancer Institute-Downriver
Brownstown, Michigan, 48183
United States
Trinity Health IHA Medical Group Hematology Oncology - Canton
Canton, Michigan, 48188
United States
Trinity Health Medical Center - Canton
Canton, Michigan, 48188
United States
Caro Cancer Center
Caro, Michigan, 48723
United States
Chelsea Hospital
Chelsea, Michigan, 48118
United States
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
Chelsea, Michigan, 48118
United States
Henry Ford Macomb Hospital-Clinton Township
Clinton Township, Michigan, 48038
United States
Corewell Health Dearborn Hospital
Dearborn, Michigan, 48124
United States
Henry Ford Hospital
Detroit, Michigan, 48202
United States
Henry Ford Health Saint John Hospital
Detroit, Michigan, 48236
United States
Corewell Health Farmington Hills Hospital
Farmington Hills, Michigan, 48336
United States
Genesys Hurley Cancer Institute
Flint, Michigan, 48503
United States
Hurley Medical Center
Flint, Michigan, 48503
United States
Henry Ford Saint John Hospital - Van Elslander
Grosse Pointe Woods, Michigan, 48236
United States
Allegiance Health
Jackson, Michigan, 49201
United States
University of Michigan Health - Sparrow Lansing
Lansing, Michigan, 48912
United States
Trinity Health Saint Mary Mercy Livonia Hospital
Livonia, Michigan, 48154
United States
Henry Ford Saint John Hospital - Macomb Medical
Macomb, Michigan, 48044
United States
Saint Mary's Oncology/Hematology Associates of Marlette
Marlette, Michigan, 48453
United States
MyMichigan Medical Center Midland
Midland, Michigan, 48670
United States
Henry Ford Health Providence Novi Hospital
Novi, Michigan, 48374
United States
Henry Ford Medical Center-Columbus
Novi, Michigan, 48377
United States
Michigan Healthcare Professionals Pontiac
Pontiac, Michigan, 48341
United States
Trinity Health Saint Joseph Mercy Oakland Hospital
Pontiac, Michigan, 48341
United States
Corewell Health William Beaumont University Hospital
Royal Oak, Michigan, 48073
United States
MyMichigan Medical Center Saginaw
Saginaw, Michigan, 48601
United States
Oncology Hematology Associates of Saginaw Valley PC
Saginaw, Michigan, 48604
United States
Henry Ford Health Providence Southfield Hospital
Southfield, Michigan, 48075
United States
MyMichigan Medical Center Tawas
Tawas City, Michigan, 48764
United States
Corewell Health Beaumont Troy Hospital
Troy, Michigan, 48085
United States
Henry Ford Health Warren Hospital
Warren, Michigan, 48093
United States
Henry Ford West Bloomfield Hospital
West Bloomfield, Michigan, 48322
United States
Saint Mary's Oncology/Hematology Associates of West Branch
West Branch, Michigan, 48661
United States
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
Ypsilanti, Michigan, 48197
United States
Sanford Joe Lueken Cancer Center
Bemidji, Minnesota, 56601
United States
Essentia Health Saint Joseph's Medical Center
Brainerd, Minnesota, 56401
United States
Minnesota Oncology - Burnsville
Burnsville, Minnesota, 55337
United States
Mercy Hospital
Coon Rapids, Minnesota, 55433
United States
Essentia Health - Deer River Clinic
Deer River, Minnesota, 56636
United States
Essentia Health Saint Mary's - Detroit Lakes Clinic
Detroit Lakes, Minnesota, 56501
United States
Essentia Health Cancer Center
Duluth, Minnesota, 55805
United States
Essentia Health Saint Mary's Medical Center
Duluth, Minnesota, 55805
United States
Miller-Dwan Hospital
Duluth, Minnesota, 55805
United States
Fairview Southdale Hospital
Edina, Minnesota, 55435
United States
Essentia Health - Fosston
Fosston, Minnesota, 56542
United States
Essentia Health Hibbing Clinic
Hibbing, Minnesota, 55746
United States
Fairview Clinics and Surgery Center Maple Grove
Maple Grove, Minnesota, 55369
United States
Minnesota Oncology Hematology PA-Maplewood
Maplewood, Minnesota, 55109
United States
Saint John's Hospital - Healtheast
Maplewood, Minnesota, 55109
United States
Abbott-Northwestern Hospital
Minneapolis, Minnesota, 55407
United States
Hennepin County Medical Center
Minneapolis, Minnesota, 55415
United States
Health Partners Inc
Minneapolis, Minnesota, 55454
United States
Monticello Cancer Center
Monticello, Minnesota, 55362
United States
Essentia Health - Park Rapids
Park Rapids, Minnesota, 56470
United States
North Memorial Medical Health Center
Robbinsdale, Minnesota, 55422
United States
Mayo Clinic in Rochester
Rochester, Minnesota, 55905
United States
Coborn Cancer Center at Saint Cloud Hospital
Saint Cloud, Minnesota, 56303
United States
Park Nicollet Clinic - Saint Louis Park
Saint Louis Park, Minnesota, 55416
United States
Regions Hospital
Saint Paul, Minnesota, 55101
United States
United Hospital
Saint Paul, Minnesota, 55102
United States
Essentia Health Sandstone
Sandstone, Minnesota, 55072
United States
Saint Francis Regional Medical Center
Shakopee, Minnesota, 55379
United States
Lakeview Hospital
Stillwater, Minnesota, 55082
United States
Essentia Health Virginia Clinic
Virginia, Minnesota, 55792
United States
Ridgeview Medical Center
Waconia, Minnesota, 55387
United States
Rice Memorial Hospital
Willmar, Minnesota, 56201
United States
Minnesota Oncology Hematology PA-Woodbury
Woodbury, Minnesota, 55125
United States
Baptist Memorial Hospital and Cancer Center-Golden Triangle
Columbus, Mississippi, 39705
United States
Baptist Cancer Center-Grenada
Grenada, Mississippi, 38901
United States
Baptist Memorial Hospital and Cancer Center-Union County
New Albany, Mississippi, 38652
United States
Baptist Memorial Hospital and Cancer Center-Oxford
Oxford, Mississippi, 38655
United States
Baptist Memorial Hospital and Cancer Center-Desoto
Southhaven, Mississippi, 38671
United States
Central Care Cancer Center - Bolivar
Bolivar, Missouri, 65613
United States
Mercy Cancer Center - Cape Girardeau
Cape Girardeau, Missouri, 63703
United States
Saint Francis Medical Center
Cape Girardeau, Missouri, 63703
United States
Parkland Health Center - Farmington
Farmington, Missouri, 63640
United States
MU Health Care Goldschmidt Cancer Center
Jefferson City, Missouri, 65109
United States
Freeman Health System
Joplin, Missouri, 64804
United States
Mercy Hospital Joplin
Joplin, Missouri, 64804
United States
Lake Regional Hospital
Osage Beach, Missouri, 65065
United States
Mercy Clinic-Rolla-Cancer and Hematology
Rolla, Missouri, 65401
United States
Phelps Health Delbert Day Cancer Institute
Rolla, Missouri, 65401
United States
Heartland Regional Medical Center
Saint Joseph, Missouri, 64506
United States
Sainte Genevieve County Memorial Hospital
Sainte Genevieve, Missouri, 63670
United States
Mercy Hospital Springfield
Springfield, Missouri, 65804
United States
CoxHealth South Hospital
Springfield, Missouri, 65807
United States
Mercy Hospital South
St Louis, Missouri, 63128
United States
Missouri Baptist Medical Center
St Louis, Missouri, 63131
United States
Mercy Hospital Saint Louis
St Louis, Missouri, 63141
United States
Missouri Baptist Sullivan Hospital
Sullivan, Missouri, 63080
United States
BJC Outpatient Center at Sunset Hills
Sunset Hills, Missouri, 63127
United States
Billings Clinic Cancer Center
Billings, Montana, 59101
United States
Bozeman Health Deaconess Hospital
Bozeman, Montana, 59715
United States
Saint James Community Hospital and Cancer Treatment Center
Butte, Montana, 59701
United States
Benefis Sletten Cancer Institute
Great Falls, Montana, 59405
United States
Great Falls Clinic
Great Falls, Montana, 59405
United States
Hi-Line Sletten Cancer Center
Havre, Montana, 59501
United States
Logan Health Medical Center
Kalispell, Montana, 59901
United States
Saint Patrick Hospital - Community Hospital
Missoula, Montana, 59802
United States
Community Medical Center
Missoula, Montana, 59804
United States
CHI Health Good Samaritan
Kearney, Nebraska, 68847
United States
Alegent Health Immanuel Medical Center
Omaha, Nebraska, 68122
United States
Alegent Health Bergan Mercy Medical Center
Omaha, Nebraska, 68124
United States
Alegent Health Lakeside Hospital
Omaha, Nebraska, 68130
United States
Creighton University Medical Center
Omaha, Nebraska, 68131
United States
Comprehensive Cancer Centers of Nevada - Henderson
Henderson, Nevada, 89052
United States
OptumCare Cancer Care at Seven Hills
Henderson, Nevada, 89052
United States
OptumCare Cancer Care at Charleston
Las Vegas, Nevada, 89102
United States
Radiation Oncology Centers of Nevada Central
Las Vegas, Nevada, 89106
United States
GenesisCare USA - Las Vegas
Las Vegas, Nevada, 89109
United States
Radiation Oncology Centers of Nevada Southeast
Las Vegas, Nevada, 89119
United States
Comprehensive Cancer Centers of Nevada - Northwest
Las Vegas, Nevada, 89128
United States
OptumCare Cancer Care at MountainView
Las Vegas, Nevada, 89128
United States
Alliance for Childhood Diseases/Cure 4 the Kids Foundation
Las Vegas, Nevada, 89135
United States
Comprehensive Cancer Centers of Nevada - Town Center
Las Vegas, Nevada, 89144
United States
Comprehensive Cancer Centers of Nevada-Summerlin
Las Vegas, Nevada, 89144
United States
Summerlin Hospital Medical Center
Las Vegas, Nevada, 89144
United States
Comprehensive Cancer Centers of Nevada
Las Vegas, Nevada, 89148
United States
GenesisCare USA - Fort Apache
Las Vegas, Nevada, 89148
United States
OptumCare Cancer Care at Fort Apache
Las Vegas, Nevada, 89148
United States
Comprehensive Cancer Centers of Nevada - Central Valley
Las Vegas, Nevada, 89169
United States
Renown Regional Medical Center
Reno, Nevada, 89502
United States
Saint Mary's Regional Medical Center
Reno, Nevada, 89503
United States
Radiation Oncology Associates
Reno, Nevada, 89509
United States
New Hampshire Oncology Hematology PA-Concord
Concord, New Hampshire, 03301
United States
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center
Lebanon, New Hampshire, 03756
United States
The Dana-Farber Cancer Institute at Londonderry
Londonderry, New Hampshire, 03053
United States
Solinsky Center for Cancer Care
Manchester, New Hampshire, 03103
United States
Memorial Sloan Kettering Basking Ridge
Basking Ridge, New Jersey, 07920
United States
Cooper Hospital University Medical Center
Camden, New Jersey, 08103
United States
Jefferson Cherry Hill Hospital
Cherry Hill, New Jersey, 08002
United States
Memorial Sloan Kettering Monmouth
Middletown, New Jersey, 07748
United States
Memorial Sloan Kettering Bergen
Montvale, New Jersey, 07645
United States
Morristown Medical Center
Morristown, New Jersey, 07960
United States
The Valley Hospital - Luckow Pavilion
Paramus, New Jersey, 07652
United States
Chilton Medical Center
Pompton, New Jersey, 07444
United States
Valley Health System Ridgewood Campus
Ridgewood, New Jersey, 07450
United States
Sidney Kimmel Cancer Center Washington Township
Sewell, New Jersey, 08080
United States
Overlook Hospital
Summit, New Jersey, 07902
United States
Holy Name Hospital
Teaneck, New Jersey, 07666
United States
Valley Health System-Hematology/Oncology
Westwood, New Jersey, 07675
United States
University of New Mexico Cancer Center
Albuquerque, New Mexico, 87106
United States
New York-Presbyterian/Brooklyn Methodist Hospital
Brooklyn, New York, 11215
United States
NYU Langone Hospital - Brooklyn
Brooklyn, New York, 11220
United States
Roswell Park Cancer Institute
Buffalo, New York, 14263
United States
Memorial Sloan Kettering Commack
Commack, New York, 11725
United States
The New York Hospital Medical Center of Queens
Flushing, New York, 11355
United States
Northwell Health Physicians Partners Radiation Medicine at Queens
Forest Hills, New York, 11375
United States
Glens Falls Hospital
Glens Falls, New York, 12801
United States
Northwell Health Cancer Institute at Huntington
Greenlawn, New York, 11740
United States
Memorial Sloan Kettering Westchester
Harrison, New York, 10604
United States
Northwell Health/Center for Advanced Medicine
Lake Success, New York, 11042
United States
North Shore University Hospital
Manhasset, New York, 11030
United States
Garnet Health Medical Center
Middletown, New York, 10940
United States
NYU Langone Hospital - Long Island
Mineola, New York, 11501
United States
Northern Westchester Hospital
Mount Kisco, New York, 10549
United States
Long Island Jewish Medical Center
New Hyde Park, New York, 11040
United States
Laura and Isaac Perlmutter Cancer Center at NYU Langone
New York, New York, 10016
United States
Mount Sinai West
New York, New York, 10019
United States
Mount Sinai Hospital
New York, New York, 10029
United States
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
New York, New York, 10032
United States
Manhattan Eye Ear and Throat Hospital
New York, New York, 10065
United States
Memorial Sloan Kettering Cancer Center
New York, New York, 10065
United States
NYP/Weill Cornell Medical Center
New York, New York, 10065
United States
Lenox Hill Hospital
New York, New York, 10075
United States
Upstate Cancer Center at Oswego
Oswego, New York, 13126
United States
Queens Cancer Center
Rego Park, New York, 11374
United States
University of Rochester
Rochester, New York, 14642
United States
Phelps Memorial Hospital Center
Sleepy Hollow, New York, 10591
United States
State University of New York Upstate Medical University
Syracuse, New York, 13210
United States
SUNY Upstate Medical Center-Community Campus
Syracuse, New York, 13215
United States
Montefiore Medical Center-Einstein Campus
The Bronx, New York, 10461
United States
Montefiore Medical Center-Weiler Hospital
The Bronx, New York, 10461
United States
Montefiore Medical Center - Moses Campus
The Bronx, New York, 10467
United States
Memorial Sloan Kettering Nassau
Uniondale, New York, 11553
United States
Upstate Cancer Center at Verona
Verona, New York, 13478
United States
Wilmot Cancer Institute at Webster
Webster, New York, 14580
United States
Atrium Health Stanly/LCI-Albemarle
Albemarle, North Carolina, 28002
United States
Duke Cancer Center Cary
Cary, North Carolina, 27518
United States
UNC Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, 27599
United States
Carolinas Medical Center/Levine Cancer Institute
Charlotte, North Carolina, 28203
United States
Atrium Health Pineville/LCI-Pineville
Charlotte, North Carolina, 28210
United States
Levine Cancer Institute-SouthPark
Charlotte, North Carolina, 28211
United States
Atrium Health University City/LCI-University
Charlotte, North Carolina, 28262
United States
Levine Cancer Institute-Ballantyne
Charlotte, North Carolina, 28277
United States
Wake Forest University at Clemmons
Clemmons, North Carolina, 27012
United States
Atrium Health Cabarrus/LCI-Concord
Concord, North Carolina, 28025
United States
Duke University Medical Center
Durham, North Carolina, 27710
United States
Levine Cancer Institute - Rutherford
Forest City, North Carolina, 28043
United States
Levine Cancer Institute-Gaston
Gastonia, North Carolina, 28054
United States
East Carolina University
Greenville, North Carolina, 27834
United States
Hayworth Cancer Center
High Point, North Carolina, 27262
United States
University of North Carolina-Hillsborough Campus
Hillsborough, North Carolina, 27278
United States
Atrium Health Lincoln/LCI-Lincolnton
Lincolnton, North Carolina, 28092
United States
Levine Cancer Institute - Union West
Matthews, North Carolina, 28104
United States
Atrium Health Union/LCI-Union
Monroe, North Carolina, 28112
United States
Duke Cancer Center Raleigh
Raleigh, North Carolina, 27609
United States
Atrium Health Cleveland/LCI-Cleveland
Shelby, North Carolina, 28150
United States
Wake Forest Baptist Health - Wilkes Medical Center
Wilkesboro, North Carolina, 28659
United States
Wake Forest University Health Sciences
Winston-Salem, North Carolina, 27157
United States
Sanford Bismarck Medical Center
Bismarck, North Dakota, 58501
United States
Essentia Health Cancer Center-South University Clinic
Fargo, North Dakota, 58103
United States
Sanford Broadway Medical Center
Fargo, North Dakota, 58122
United States
Sanford Roger Maris Cancer Center
Fargo, North Dakota, 58122
United States
Essentia Health - Jamestown Clinic
Jamestown, North Dakota, 58401
United States
Indu and Raj Soin Medical Center
Beavercreek, Ohio, 45431
United States
Saint Elizabeth Boardman Hospital
Boardman, Ohio, 44512
United States
Aultman Health Foundation
Canton, Ohio, 44710
United States
Dayton Physicians LLC-Miami Valley South
Centerville, Ohio, 45459
United States
Good Samaritan Hospital - Cincinnati
Cincinnati, Ohio, 45220
United States
Oncology Hematology Care Inc-Kenwood
Cincinnati, Ohio, 45236
United States
Bethesda North Hospital
Cincinnati, Ohio, 45242
United States
MetroHealth Medical Center
Cleveland, Ohio, 44109
United States
Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210
United States
Dayton Physician LLC - Englewood
Dayton, Ohio, 45415
United States
Armes Family Cancer Center
Findlay, Ohio, 45840
United States
Blanchard Valley Hospital
Findlay, Ohio, 45840
United States
Orion Cancer Care
Findlay, Ohio, 45840
United States
Dayton Physicians LLC-Atrium
Franklin, Ohio, 45005
United States
Dayton Physicians LLC-Wayne
Greenville, Ohio, 45331
United States
Wayne Hospital
Greenville, Ohio, 45331
United States
Greater Dayton Cancer Center
Kettering, Ohio, 45409
United States
Kettering Medical Center
Kettering, Ohio, 45429
United States
Dayton Physicians LLC - Troy
Troy, Ohio, 45373
United States
Saint Joseph Warren Hospital
Warren, Ohio, 44484
United States
Saint Elizabeth Youngstown Hospital
Youngstown, Ohio, 44501
United States
University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, 73104
United States
Mercy Hospital Oklahoma City
Oklahoma City, Oklahoma, 73120
United States
Saint Charles Health System
Bend, Oregon, 97701
United States
Clackamas Radiation Oncology Center
Clackamas, Oregon, 97015
United States
Providence Cancer Institute Clackamas Clinic
Clackamas, Oregon, 97015
United States
Bay Area Hospital
Coos Bay, Oregon, 97420
United States
Legacy Mount Hood Medical Center
Gresham, Oregon, 97030
United States
Providence Newberg Medical Center
Newberg, Oregon, 97132
United States
Providence Willamette Falls Medical Center
Oregon City, Oregon, 97045
United States
Legacy Good Samaritan Hospital and Medical Center
Portland, Oregon, 97210
United States
Providence Portland Medical Center
Portland, Oregon, 97213
United States
Providence Saint Vincent Medical Center
Portland, Oregon, 97225
United States
Legacy Meridian Park Hospital
Tualatin, Oregon, 97062
United States
Lehigh Valley Hospital-Cedar Crest
Allentown, Pennsylvania, 18103
United States
UPMC Altoona
Altoona, Pennsylvania, 16601
United States
UPMC-Heritage Valley Health System Beaver
Beaver, Pennsylvania, 15009
United States
Lehigh Valley Hospital - Muhlenberg
Bethlehem, Pennsylvania, 18017
United States
UPMC Camp Hill
Camp Hill, Pennsylvania, 17011
United States
Carlisle Regional Cancer Center
Carlisle, Pennsylvania, 17015
United States
Christiana Care Health System-Concord Health Center
Chadds Ford, Pennsylvania, 19317
United States
Pocono Medical Center
East Stroudsburg, Pennsylvania, 18301
United States
UPMC Hillman Cancer Center Erie
Erie, Pennsylvania, 16505
United States
Saint Vincent Hospital
Erie, Pennsylvania, 16544
United States
UPMC Cancer Center at UPMC Horizon
Farrell, Pennsylvania, 16121
United States
UPMC Cancer Centers - Arnold Palmer Pavilion
Greensburg, Pennsylvania, 15601
United States
UPMC Hillman Cancer Center in Greenville/UPMC Horizon
Greenville, Pennsylvania, 16125
United States
UPMC Pinnacle Cancer Center/Community Osteopathic Campus
Harrisburg, Pennsylvania, 17109
United States
Penn State Milton S Hershey Medical Center
Hershey, Pennsylvania, 17033-0850
United States
IRMC Cancer Center
Indiana, Pennsylvania, 15701
United States
Jefferson Hospital
Jefferson Hills, Pennsylvania, 15025
United States
UPMC-Johnstown/John P. Murtha Regional Cancer Center
Johnstown, Pennsylvania, 15901
United States
UPMC Cancer Center at UPMC McKeesport
McKeesport, Pennsylvania, 15132
United States
UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion
Mechanicsburg, Pennsylvania, 17050
United States
Forbes Hospital
Monroeville, Pennsylvania, 15146
United States
UPMC Cancer Center - Monroeville
Monroeville, Pennsylvania, 15146
United States
UPMC Hillman Cancer Center - Monroeville
Monroeville, Pennsylvania, 15146
United States
UPMC Hillman Cancer Center in Coraopolis
Moon Township, Pennsylvania, 15108
United States
UPMC Hillman Cancer Center - Part of Frick Hospital
Mount Pleasant, Pennsylvania, 15666
United States
Arnold Palmer Cancer Center Medical Oncology Norwin
N. Huntingdon, Pennsylvania, 15642
United States
UPMC Cancer Center-Natrona Heights
Natrona Heights, Pennsylvania, 15065
United States
UPMC Hillman Cancer Center - New Castle
New Castle, Pennsylvania, 16105
United States
Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, 19107
United States
Jefferson Torresdale Hospital
Philadelphia, Pennsylvania, 19114
United States
Allegheny General Hospital
Pittsburgh, Pennsylvania, 15212
United States
UPMC-Magee Womens Hospital
Pittsburgh, Pennsylvania, 15213
United States
UPMC-Saint Margaret
Pittsburgh, Pennsylvania, 15215
United States
UPMC-Mercy Hospital
Pittsburgh, Pennsylvania, 15219
United States
West Penn Hospital
Pittsburgh, Pennsylvania, 15224
United States
University of Pittsburgh Cancer Institute (UPCI)
Pittsburgh, Pennsylvania, 15232
United States
UPMC-Shadyside Hospital
Pittsburgh, Pennsylvania, 15232
United States
UPMC-Passavant Hospital
Pittsburgh, Pennsylvania, 15237
United States
UPMC-Saint Clair Hospital Cancer Center
Pittsburgh, Pennsylvania, 15243
United States
UPMC Cancer Center at UPMC Northwest
Seneca, Pennsylvania, 16346
United States
UPMC Cancer Center-Uniontown
Uniontown, Pennsylvania, 15401
United States
UPMC Uniontown Hospital Radiation Oncology
Uniontown, Pennsylvania, 15401
United States
UPMC Cancer Center-Washington
Washington, Pennsylvania, 15301
United States
UPMC Washington Hospital Radiation Oncology
Washington, Pennsylvania, 15301
United States
Chester County Hospital
West Chester, Pennsylvania, 19380
United States
Reading Hospital
West Reading, Pennsylvania, 19611
United States
Wexford Health and Wellness Pavilion
Wexford, Pennsylvania, 15090
United States
Divine Providence Hospital
Williamsport, Pennsylvania, 17754
United States
Asplundh Cancer Pavilion
Willow Grove, Pennsylvania, 19090
United States
UPMC Memorial
York, Pennsylvania, 17408
United States
AnMed Health Cancer Center
Anderson, South Carolina, 29621
United States
Medical University of South Carolina
Charleston, South Carolina, 29425
United States
Gibbs Cancer Center-Gaffney
Gaffney, South Carolina, 29341
United States
Tidelands Georgetown Memorial Hospital
Georgetown, South Carolina, 29440
United States
Prisma Health Cancer Institute - Faris
Greenville, South Carolina, 29605
United States
Prisma Health Cancer Institute - Eastside
Greenville, South Carolina, 29615
United States
Prisma Health Cancer Institute - Greer
Greer, South Carolina, 29650
United States
Gibbs Cancer Center-Pelham
Greer, South Carolina, 29651
United States
MUSC Health Tidelands Health Radiation Therapy Center
Murrells Inlet, South Carolina, 29576
United States
Rock Hill Radiation Therapy Center
Rock Hill, South Carolina, 29730
United States
Levine Cancer Institute-Rock Hill
Rock Hill, South Carolina, 29732
United States
Prisma Health Cancer Institute - Seneca
Seneca, South Carolina, 29672
United States
Spartanburg Medical Center
Spartanburg, South Carolina, 29303
United States
SMC Center for Hematology Oncology Union
Union, South Carolina, 29379
United States
Lexington Medical Center
West Columbia, South Carolina, 29169
United States
Avera Cancer Institute-Aberdeen
Aberdeen, South Dakota, 57401
United States
Avera Cancer Institute - Mitchell
Mitchell, South Dakota, 57301
United States
Avera Cancer Institute at Pierre
Pierre, South Dakota, 57501
United States
Sanford Cancer Center Oncology Clinic
Sioux Falls, South Dakota, 57104
United States
Avera Cancer Institute
Sioux Falls, South Dakota, 57105
United States
Sanford USD Medical Center - Sioux Falls
Sioux Falls, South Dakota, 57117-5134
United States
Avera Cancer Institute at Yankton
Yankton, South Dakota, 57078
United States
Baptist Memorial Hospital and Cancer Center-Collierville
Collierville, Tennessee, 38017
United States
The West Clinic - Wolf River
Germantown, Tennessee, 38138
United States
Baptist Memorial Hospital and Cancer Center-Memphis
Memphis, Tennessee, 38120
United States
Vanderbilt Breast Center at One Hundred Oaks
Nashville, Tennessee, 37204
United States
Vanderbilt University/Ingram Cancer Center
Nashville, Tennessee, 37232
United States
The Don and Sybil Harrington Cancer Center
Amarillo, Texas, 79106
United States
MD Anderson in The Woodlands
Conroe, Texas, 77384
United States
Parkland Memorial Hospital
Dallas, Texas, 75235
United States
UT Southwestern Simmons Cancer Center - RedBird
Dallas, Texas, 75237
United States
UT Southwestern/Simmons Cancer Center-Dallas
Dallas, Texas, 75390
United States
Tarrant County Hospital District/JPS Health Network
Fort Worth, Texas, 76104
United States
UT Southwestern/Simmons Cancer Center-Fort Worth
Fort Worth, Texas, 76104
United States
Lyndon Baines Johnson General Hospital
Houston, Texas, 77026-1967
United States
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
Houston, Texas, 77030
United States
Ben Taub General Hospital
Houston, Texas, 77030
United States
M D Anderson Cancer Center
Houston, Texas, 77030
United States
MD Anderson West Houston
Houston, Texas, 77079
United States
MD Anderson League City
League City, Texas, 77573
United States
UT Southwestern Clinical Center at Richardson/Plano
Richardson, Texas, 75080
United States
Scott and White Healthcare Round Rock
Round Rock, Texas, 78665
United States
University of Texas Health Science Center at San Antonio
San Antonio, Texas, 78229
United States
MD Anderson in Sugar Land
Sugar Land, Texas, 77478
United States
Scott and White Memorial Hospital
Temple, Texas, 76508
United States
Farmington Health Center
Farmington, Utah, 84025
United States
University of Utah Sugarhouse Health Center
Salt Lake City, Utah, 84106
United States
Huntsman Cancer Institute/University of Utah
Salt Lake City, Utah, 84112
United States
Central Vermont Medical Center/National Life Cancer Treatment
Berlin Corners, Vermont, 05602
United States
University of Vermont Medical Center
Burlington, Vermont, 05401
United States
University of Vermont and State Agricultural College
Burlington, Vermont, 05405
United States
University of Virginia Cancer Center
Charlottesville, Virginia, 22908
United States
Inova Schar Cancer Institute
Fairfax, Virginia, 22031
United States
Inova Fair Oaks Hospital
Fairfax, Virginia, 22033
United States
Inova Fairfax Hospital
Falls Church, Virginia, 22042
United States
Inova Loudoun Hospital
Leesburg, Virginia, 20176
United States
Sovah Health Martinsville
Martinsville, Virginia, 24112
United States
Virginia Cancer Institute
Richmond, Virginia, 23229
United States
VCU Massey Cancer Center at Stony Point
Richmond, Virginia, 23235
United States
VCU Massey Comprehensive Cancer Center
Richmond, Virginia, 23298
United States
Providence Regional Cancer System-Aberdeen
Aberdeen, Washington, 98520
United States
PeaceHealth Saint Joseph Medical Center
Bellingham, Washington, 98225
United States
Providence Regional Cancer System-Centralia
Centralia, Washington, 98531
United States
Swedish Cancer Institute-Edmonds
Edmonds, Washington, 98026
United States
Providence Regional Cancer Partnership
Everett, Washington, 98201
United States
Swedish Cancer Institute-Issaquah
Issaquah, Washington, 98029
United States
Kadlec Clinic Hematology and Oncology
Kennewick, Washington, 99336
United States
FHCC at EvergreenHealth
Kirkland, Washington, 98034
United States
Providence Regional Cancer System-Lacey
Lacey, Washington, 98503
United States
PeaceHealth Saint John Medical Center
Longview, Washington, 98632
United States
Skagit Regional Health Cancer Care Center
Mount Vernon, Washington, 98274
United States
Valley Medical Center
Renton, Washington, 98055
United States
Virginia Mason Medical Center
Seattle, Washington, 98101
United States
Swedish Medical Center-Ballard Campus
Seattle, Washington, 98107
United States
Fred Hutchinson Cancer Center
Seattle, Washington, 98109
United States
Swedish Medical Center-First Hill
Seattle, Washington, 98122
United States
University of Washington Medical Center - Montlake
Seattle, Washington, 98195
United States
PeaceHealth United General Medical Center
Sedro-Woolley, Washington, 98284
United States
Saint Michael Cancer Center
Silverdale, Washington, 98383
United States
PeaceHealth Southwest Medical Center
Vancouver, Washington, 98664
United States
Legacy Cancer Institute Medical Oncology and Day Treatment
Vancouver, Washington, 98684
United States
Legacy Salmon Creek Hospital
Vancouver, Washington, 98686
United States
Providence Saint Mary Regional Cancer Center
Walla Walla, Washington, 99362
United States
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital
Yakima, Washington, 98902
United States
United Hospital Center
Bridgeport, West Virginia, 26330
United States
West Virginia University Healthcare
Morgantown, West Virginia, 26506
United States
Camden Clark Medical Center
Parkersburg, West Virginia, 26101
United States
Langlade Hospital and Cancer Center
Antigo, Wisconsin, 54409
United States
Duluth Clinic Ashland
Ashland, Wisconsin, 54806
United States
Northwest Wisconsin Cancer Center
Ashland, Wisconsin, 54806
United States
Aurora Cancer Care-Southern Lakes VLCC
Burlington, Wisconsin, 53105
United States
Marshfield Medical Center-EC Cancer Center
Eau Claire, Wisconsin, 54701
United States
Aurora Health Care Germantown Health Center
Germantown, Wisconsin, 53022
United States
Aurora Cancer Care-Grafton
Grafton, Wisconsin, 53024
United States
Saint Vincent Hospital Cancer Center Green Bay
Green Bay, Wisconsin, 54301
United States
Saint Vincent Hospital Cancer Center at Saint Mary's
Green Bay, Wisconsin, 54303
United States
Aurora BayCare Medical Center
Green Bay, Wisconsin, 54311
United States
Essentia Health-Hayward Clinic
Hayward, Wisconsin, 54843
United States
Aurora Cancer Care-Kenosha South
Kenosha, Wisconsin, 53142
United States
Aurora Bay Area Medical Group-Marinette
Marinette, Wisconsin, 54143
United States
Marshfield Medical Center-Marshfield
Marshfield, Wisconsin, 54449
United States
Aspirus Medford Hospital
Medford, Wisconsin, 54451
United States
Froedtert Menomonee Falls Hospital
Menomonee Falls, Wisconsin, 53051
United States
Aurora Cancer Care-Milwaukee
Milwaukee, Wisconsin, 53209
United States
Aurora Saint Luke's Medical Center
Milwaukee, Wisconsin, 53215
United States
Medical College of Wisconsin
Milwaukee, Wisconsin, 53226
United States
Aurora Sinai Medical Center
Milwaukee, Wisconsin, 53233
United States
Marshfield Medical Center - Minocqua
Minocqua, Wisconsin, 54548
United States
ProHealth D N Greenwald Center
Mukwonago, Wisconsin, 53149
United States
Cancer Center of Western Wisconsin
New Richmond, Wisconsin, 54017
United States
Drexel Town Square Health Center
Oak Creek, Wisconsin, 53154
United States
ProHealth Oconomowoc Memorial Hospital
Oconomowoc, Wisconsin, 53066
United States
Vince Lombardi Cancer Clinic - Oshkosh
Oshkosh, Wisconsin, 54904
United States
Aurora Cancer Care-Racine
Racine, Wisconsin, 53406
United States
Aspirus Cancer Care - James Beck Cancer Center
Rhinelander, Wisconsin, 54501
United States
Marshfield Medical Center-Rice Lake
Rice Lake, Wisconsin, 54868
United States
Saint Vincent Hospital Cancer Center at Sheboygan
Sheboygan, Wisconsin, 53081
United States
Vince Lombardi Cancer Clinic-Sheboygan
Sheboygan, Wisconsin, 53081
United States
Essentia Health-Spooner Clinic
Spooner, Wisconsin, 54801
United States
Aspirus Cancer Care - Stevens Point
Stevens Point, Wisconsin, 54481
United States
Marshfield Medical Center-River Region at Stevens Point
Stevens Point, Wisconsin, 54482
United States
Saint Vincent Hospital Cancer Center at Sturgeon Bay
Sturgeon Bay, Wisconsin, 54235-1495
United States
Aurora Medical Center in Summit
Summit, Wisconsin, 53066
United States
Essentia Health Saint Mary's Hospital - Superior
Superior, Wisconsin, 54880
United States
Vince Lombardi Cancer Clinic-Two Rivers
Two Rivers, Wisconsin, 54241
United States
UW Cancer Center at ProHealth Care
Waukesha, Wisconsin, 53188
United States
Aspirus Regional Cancer Center
Wausau, Wisconsin, 54401
United States
Aurora Cancer Care-Milwaukee West
Wauwatosa, Wisconsin, 53226
United States
Aurora West Allis Medical Center
West Allis, Wisconsin, 53227
United States
Froedtert West Bend Hospital/Kraemer Cancer Center
West Bend, Wisconsin, 53095
United States
Marshfield Medical Center - Weston
Weston, Wisconsin, 54476
United States
Aspirus Cancer Care - Wisconsin Rapids
Wisconsin Rapids, Wisconsin, 54494
United States
Welch Cancer Center
Sheridan, Wyoming, 82801
United States

Collaborators and Investigators

Sponsor: Alliance for Clinical Trials in Oncology

  • J. Joshua Smith, MD, STUDY_CHAIR, Memorial Sloan Kettering Cancer Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-12-08
Study Completion Date2032-09-30

Study Record Updates

Study Start Date2022-12-08
Study Completion Date2032-09-30

Terms related to this study

Additional Relevant MeSH Terms

  • Locally Advanced Rectal Carcinoma
  • Stage II Rectal Cancer AJCC v8
  • Stage III Rectal Cancer AJCC v8