RECRUITING

Patients with and Without Phonotrauma

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

There is a substantial need to identify objective measures associated with hyperadduction of the vocal folds to recognize those at higher risk of developing phonotrauma so that risk mitigation strategies can be implemented before phonotrauma develops. The overall objective of this proposed project is to investigate the sensitivity and direction of change in cepstral peak prominence (CPP) and the magnitude difference between the first two harmonics of the voice spectrum (H1-H2) in response to varied phonation patterns, which will be addressed using the following two aims: Aim 1: Determine how CPP and H1-H2 change as a function of using pressed voice production in individuals without laryngeal pathology. Aim 2: Examine the sensitivity (minimally detectable change) and responsiveness (minimal clinically important difference) of CPP and H1-H2 to detect changes in different voice production conditions.

Official Title

Defining Clinically Important Differences in Cepstral and Spectral Measures in Individuals with and Without Phonotrauma

Quick Facts

Study Start:2023-01-17
Study Completion:2025-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05625191

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. 18-65 years of age (to avoid confounding physiological factors related to puberty or presbyphonia)
  2. 2. No history of or current voice disorder
  3. 3. Auditory perceptual presentation globally within functional limits (as determined by a voice specialized SLP).
  1. 1. Atypical auditory-perceptual voice presentation
  2. 2. History of voice disorder or laryngeal surgery.

Contacts and Locations

Study Contact

Laura Toles, PhD
CONTACT
214-645-2943
Laura.Toles@UTSouthwestern.edu
Paula Arellano-Cruz
CONTACT
214-648-8096
paula.arellano-cruz@utsouthwestern.edu

Study Locations (Sites)

UT Southwestern Medical Center
Dallas, Texas, 75235
United States

Collaborators and Investigators

Sponsor: University of Texas Southwestern Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-01-17
Study Completion Date2025-06-30

Study Record Updates

Study Start Date2023-01-17
Study Completion Date2025-06-30

Terms related to this study

Additional Relevant MeSH Terms

  • Phonotrauma