RECRUITING

Autonomic Effects of Stimulation in SCI

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study aims to determine the effects of transcutaneous spinal cord stimulation to increase blood pressure and use that device to increase power output and heart rate recovery during arm cycle ergometry. In addition, the investigators will see if the stimulation helps regulate body temperature when in a cool environment.

Official Title

Autonomic Effects of Transcutaneous Spinal Cord Stimulation in Veterans With SCI

Quick Facts

Study Start:2023-07-24
Study Completion:2026-07-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05664646

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * injury more than 1 year ago, non-ambulatory
  2. * level of lesion C3-T6, AIS A, B, or C
  3. * stable prescription medication regimen for at least 30 days
  4. * must be able to commit to study requirements of 7 visits within a 60-day period
  1. * extensive history of seizures
  2. * ventilator dependence or patent tracheostomy site
  3. * history of neurologic disorder other than SCI
  4. * history of moderate or severe head trauma
  5. * contraindications to spine stimulation
  6. * significant cardiovascular disease
  7. * active psychological disorder
  8. * recent history (within 3 months) of substance abuse
  9. * open skin lesions over spine at levels targeted for stimulation (L1/L2) and pregnancy

Contacts and Locations

Study Contact

Jill Wecht, EdD
CONTACT
(718) 584-9000
jm.wecht@va.gov
Matthew T Maher, MS
CONTACT
(718) 584-9000
matthew.maher@va.gov

Principal Investigator

Jill Wecht, EdD
PRINCIPAL_INVESTIGATOR
James J. Peters Veterans Affairs Medical Center

Study Locations (Sites)

James J. Peters VA Medical Center, Bronx, NY
Bronx, New York, 10468-3904
United States

Collaborators and Investigators

Sponsor: VA Office of Research and Development

  • Jill Wecht, EdD, PRINCIPAL_INVESTIGATOR, James J. Peters Veterans Affairs Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-07-24
Study Completion Date2026-07-30

Study Record Updates

Study Start Date2023-07-24
Study Completion Date2026-07-30

Terms related to this study

Keywords Provided by Researchers

  • Orthostatic Hypotension
  • Exercise
  • Hypotension
  • Body Core Temperature
  • Blood Pressure

Additional Relevant MeSH Terms

  • Spinal Cord Injury