RECRUITING

Speech Signals in Stuttering

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this research study is to understand how speech and language are processed in the brain. This study will provide information that may help with the understanding how speech and language are processed in children and whether there may be differences between children who stutter and children who do not stutter. This project will evaluate these neural processes for speech signals in children who stutter and control subjects through a battery of behavioral speech and language tests, electroencephalography-based (EEG) tasks, functional magnetic resonance imaging (fMRI), and computational modeling.

Official Title

Neural Processing of Speech Signals in Children Who Stutter

Quick Facts

Study Start:2022-09-21
Study Completion:2027-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05668923

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:5 Years to 17 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD
Inclusion CriteriaExclusion Criteria
  1. * Speaks English as primary language
  2. * Language abilities within the typical range
  3. * Cognitive abilities within the typical range
  4. * No contraindications for MRI
  5. * Presence of developmental stuttering (onset in childhood)
  6. * No history of other communication disorder
  7. * No family history of stuttering
  8. * No history of other communication disorders (e.g., hearing impairment, language impairment, cognitive impairment/injury)
  1. * Taking medication that alters neural function
  2. * Cognitive skills below the typical range
  3. * Major medical illness
  4. * Not a fluent speaker of English
  5. * Pregnant or possibly pregnant
  6. * Metal implants in your body (including pacemakers, neurostimulators, or other metal objects)
  7. * Shrapnel injuries
  8. * Ocular foreign bodies (e.g., metal shavings)
  9. * Metal piercings that cannot be removed for the scan
  10. * Tattoos containing iron or metal pigments
  11. * Prone to claustrophobia
  12. * For fMRI, those with head circumference greater than 60cm or whose weight is more than 300 pounds will be excluded due to the size of the fMRI magnet bore

Contacts and Locations

Study Contact

Brittany Coleman, MS, CCC-SLP
CONTACT
412-710-6028
bmc162@pitt.edu
Ashley Parker, PhD
CONTACT
412-710-6028
ashley.parker@pitt.edu

Principal Investigator

Amanda Hampton Wray, PhD, CCC-SLP
PRINCIPAL_INVESTIGATOR
University of Pittsburgh

Study Locations (Sites)

University of Michigan
Ann Arbor, Michigan, 48105
United States
University of Pittsburgh
Pittsburgh, Pennsylvania, 15213
United States

Collaborators and Investigators

Sponsor: University of Pittsburgh

  • Amanda Hampton Wray, PhD, CCC-SLP, PRINCIPAL_INVESTIGATOR, University of Pittsburgh

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-09-21
Study Completion Date2027-12

Study Record Updates

Study Start Date2022-09-21
Study Completion Date2027-12

Terms related to this study

Additional Relevant MeSH Terms

  • Stuttering, Childhood