RECRUITING

Comparing the Adaptation of Commercial Milk and A2 Milk in Lactose Maldigesters

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Cow's milk contains two types of β-casein: A1 and A2. It is evident from human clinical trials that milk with A1 protein produces more hydrogen and symptoms of lactose intolerance. A pro-inflammatory μ-opioid peptide BCM-7 is released from A1 but not from A2. Milk containing A1 β-casein produced more inflammatory markers than A2 β-casein. This is a double-blinded, randomized, controlled trial conducted to determine if there are changes in inflammatory markers following two weeks of milk feeding, due to milk containing A1 and A2 beta-casein as compared to milk containing only A2 beta-casein.

Official Title

Comparing Inflammation, Lactose Intolerance and Lactose Maldigestion in Lactose Maldigesters on Consumption of Commercial Milk Containing A1 and A2 Beta-Casein and A2 Milk Containing Only A2 Beta-Casein for Two Weeks

Quick Facts

Study Start:2021-12-02
Study Completion:2025-12-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05669274

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Ability/desire to provide informed consent Aged 18 to 65 years of age inclusive at screening Current or recent history of intolerance to or avoidance of dairy of at least one month duration (by self-report and self-reported symptoms).
  1. * Allergic to milk

Contacts and Locations

Study Contact

Dennis Savaiano, PhD
CONTACT
765-494-8228
savaiano@purdue.edu
Tracy Eaton, MSW
CONTACT
tkeaton@purdue.edu

Principal Investigator

Dennis Savaiano, PhD
PRINCIPAL_INVESTIGATOR
Purdue University

Study Locations (Sites)

Purdue University
West Lafayette, Indiana, 47907
United States

Collaborators and Investigators

Sponsor: Purdue University

  • Dennis Savaiano, PhD, PRINCIPAL_INVESTIGATOR, Purdue University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-12-02
Study Completion Date2025-12-06

Study Record Updates

Study Start Date2021-12-02
Study Completion Date2025-12-06

Terms related to this study

Additional Relevant MeSH Terms

  • Lactose Intolerance