Brief Summary: This study will test the safety, including side effects, and determine the characteristics of a drug called PRO1160 in participants with solid tumors. Participants will have solid tumor or liquid cancer that has spread through the body (metastatic) or cannot be removed with surgery (unresectable). This Phase 1/2 study will have two parts. Part A of the study will find out how much and how frequently PRO1160 should be given to participants. Part B will use the dose and schedule found in Part A to find out how safe PRO1160 is and if it works to treat the diseases under study. The diseases under study will be Renal Cell Carcinoma (RCC),Nasopharyngeal Carcinoma (NPC) and Non-Hodgkin Lymphoma (NHL).
Brief Summary: This study will test the safety, including side effects, and determine the characteristics of a drug called PRO1160 in participants with solid tumors. Participants will have solid tumor or liquid cancer that has spread through the body (metastatic) or cannot be removed with surgery (unresectable). This Phase 1/2 study will have two parts. Part A of the study will find out how much and how frequently PRO1160 should be given to participants. Part B will use the dose and schedule found in Part A to find out how safe PRO1160 is and if it works to treat the diseases under study. The diseases under study will be Renal Cell Carcinoma (RCC),Nasopharyngeal Carcinoma (NPC) and Non-Hodgkin Lymphoma (NHL).
PRO1160 for Advanced Solid and Liquid Tumors (PRO1160-001)
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City of Hope Comprehensive Cancer Center - Duarte, Duarte, California, United States, 91010
The City of Hope Orange County Lennar Foundation Cancer Center, Irvine, California, United States, 92618
University of Michigan, Ann Arbor, Michigan, United States, 48109
Karmanos Cancer Institute, Detroit, Michigan, United States, 48201
Washington University School of Medicine in St. Louis, Saint Louis, Missouri, United States, 63110
Montefiore Medical Center - Montefiore Hospital, Bronx, New York, United States, 10467
NYU Langone Health, New York, New York, United States, 10016
Levine Cancer Center, Charlotte, North Carolina, United States, 28204
Cleveland Clinic - Euclid Hospital, Cleveland, Ohio, United States, 44195
Providence Portland Medical Center, Portland, Oregon, United States, 97213
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
18 Years to
ALL
No
ProfoundBio US Co.,
2027-03-30