RECRUITING

L-Citrulline and Endothelial Function

Description

The effect of L-Citrulline is well studied in relation to muscle strength, exhaustion, exercise performance, and endothelial function in health and disease. This study will extend current body of knowledge and will investigate the effect of L-Citrulline on brain vascular function.

Conditions

Aging
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Related Conditions:

Aging

Study Overview

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Study Details

Study overview

The effect of L-Citrulline is well studied in relation to muscle strength, exhaustion, exercise performance, and endothelial function in health and disease. This study will extend current body of knowledge and will investigate the effect of L-Citrulline on brain vascular function.

Effect of Oral L-Citrulline on the Peripheral and Central Endothelial Function in Young and Older Adults

L-Citrulline and Endothelial Function

Condition
Aging
Intervention / Treatment

-

Contacts and Locations

Oklahoma City

Andriy Yabluchanskiy, Oklahoma City, Oklahoma, United States, 73117

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age 21-45 and ≥55-90 years of age
  • * Adequate hearing and visual acuity to participate in the examinations
  • * Ability to read and write in English
  • * Competence to provide informed consent
  • * Active CNS disease including multiple sclerosis, uncontrolled seizures, active brain cancer
  • * Cerebrovascular accident other than TIA within 60 days prior to Visit 0
  • * Major psychiatric disease, including major depression not currently controlled on medications, alcohol or drug abuse
  • * Treatment with other Citrulline enhancers (L-Arginine, L-Citrulline Malate) within 4 weeks prior to Visit 0
  • * Any other medical condition which, in the opinion of investigator, would render the patient inappropriate or too unstable to complete the study protocol

Ages Eligible for Study

18 Years to 90 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Oklahoma,

Andriy Yabluchanskiy, MD, PhD, PRINCIPAL_INVESTIGATOR, University of Oklahoma

Study Record Dates

2024-12-28