RECRUITING

3D Specimen Maps for RT Planning

Description

The primary objective of this study is to measure the impact of patient-specific 3D specimen maps on adjuvant radiation treatment volumes and doses to critical organs. All patients will receive standard-of-care post-operative radiotherapy not impacted by the experimental 3D specimen maps. The secondary objective is to demonstrate the feasibility of incorporating 3D specimen mapping tools into post-operative communication, and to determine if utilization of the 3D specimen map improves post-operative communication between surgeons, pathologists, and radiation oncologists.

Conditions

Head and Neck CancerHead and Neck Squamous Cell CarcinomaRadiation Therapy
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Related Conditions:

Head and Neck CancerHead and Neck Squamous Cell CarcinomaRadiation Therapy

Study Overview

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Study Details

Study overview

The primary objective of this study is to measure the impact of patient-specific 3D specimen maps on adjuvant radiation treatment volumes and doses to critical organs. All patients will receive standard-of-care post-operative radiotherapy not impacted by the experimental 3D specimen maps. The secondary objective is to demonstrate the feasibility of incorporating 3D specimen mapping tools into post-operative communication, and to determine if utilization of the 3D specimen map improves post-operative communication between surgeons, pathologists, and radiation oncologists.

Virtual Patient-specific 3D Specimen Maps for Adjuvant Head & Neck Radiotherapy Planning

3D Specimen Maps for RT Planning

Condition
Head and Neck Cancer
Intervention / Treatment

-

Contacts and Locations

Nashville

Vanderbilt Medical Center, Nashville, Tennessee, United States, 37232

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Over the age of 18
  • 2. Biopsy-confirmed mucosal head and neck cancer. All histologic malignancies will be included.
  • 3. Patients who have completed primary tumor surgical resection in the following anatomic subsites:
  • 1. oral cavity (oral tongue, floor of mouth, hard palate, buccal mucosa, retromolar trigone, maxillary and mandibular alveolus, lip)
  • 2. oropharynx (soft palate, base of tongue, palatine tonsils)
  • 3. hypopharynx (piriform sinus, post-cricoid, posterior pharyngeal wall)
  • 4. larynx (supraglottic, glottic, subglottic);
  • 4. Patients who have consented to 3D specimen mapping on protocol IRB # 221597 and for whom 3D specimen maps are therefore available.
  • 5. Patients are indicated to receive curative-intent post-operative radiotherapy and intend to receive radiotherapy at Vanderbilt University Medical Center or Vanderbilt Ingram Cancer Center sites in Nashville, Franklin, or Lebanon
  • 1. Under the age of 18
  • 2. Cutaneous malignancies
  • 3. Characteristics that make the process of informed consent questionable
  • 4. Pregnant women
  • 5. Patients with contraindications to radiotherapy

Ages Eligible for Study

28 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Vanderbilt University Medical Center,

Study Record Dates

2024-12-26