RECRUITING

Face Perception vs. Memory Training to Improve Face Recognition in Developmental Prosopagnosia

Conditions

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this study is to test the effectiveness of two experimental training programs aimed at improving face processing in developmental prosopagnosia (perception training, memory training) in comparison to an active control. The investigators will use a longitudinal design and randomize developmental prosopagnosics to three parallel arms: active control, perception training and memory training.

Official Title

Examining the Effectiveness of Face Perception and Memory Training to Improve Face Recognition in Developmental Prosopagnosia

Quick Facts

Study Start:2023-10-15

Study Completion:2025-02-21

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT05800782

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 90 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:No

Standard Ages:ADULT, OLDER_ADULT

Inclusion Criteria	Exclusion Criteria
* Aged 18-90 * Have lifelong histories of face recognition difficulties that impact everyday life (i.e., not associated with some event such as a stroke, seizure, etc) * Score \> 2 standard deviations below the mean on the famous faces test and Cambridge Face Memory Test. This is in line with our previous studies and others in the literature.	* History of a significant neurological disorder including hydrocephalus, stroke, moderate to severe traumatic brain injury (TBI), severe neuromuscular diseases, or severe hypoxia due to cardiac arrest. * Participants with a history of mild TBI or simple concussion will not be excluded as long as it was \> 6 months ago and as long as they have not had repeated concussions (\>5). * Participants will be excluded if they have impairments that interfere with cognitive performance, such as uncorrected hearing or vision, lack of English proficiency, musculoskeletal or other issues. * Additionally, participants will be excluded if they have psychiatric disorders, such as schizophrenia, major depressive disorder, bipolar disorder, chronic intractable obsessive-compulsive disorder, or agoraphobia. * Participants with a diagnosis of ADHD will be included as long as their medication has been consistent for the past 6 months. * Participants who are currently dependent on alcohol or other substances will be excluded, as this may negatively impact cognitive performance. * Participants who currently are, or within the last 6 months, participating in a behavioral or pharmacological intervention will be excluded.

Inclusion Criteria

Exclusion Criteria

* Aged 18-90
* Have lifelong histories of face recognition difficulties that impact everyday life (i.e., not associated with some event such as a stroke, seizure, etc)
* Score \> 2 standard deviations below the mean on the famous faces test and Cambridge Face Memory Test. This is in line with our previous studies and others in the literature.

* History of a significant neurological disorder including hydrocephalus, stroke, moderate to severe traumatic brain injury (TBI), severe neuromuscular diseases, or severe hypoxia due to cardiac arrest.
* Participants with a history of mild TBI or simple concussion will not be excluded as long as it was \> 6 months ago and as long as they have not had repeated concussions (\>5).
* Participants will be excluded if they have impairments that interfere with cognitive performance, such as uncorrected hearing or vision, lack of English proficiency, musculoskeletal or other issues.
* Additionally, participants will be excluded if they have psychiatric disorders, such as schizophrenia, major depressive disorder, bipolar disorder, chronic intractable obsessive-compulsive disorder, or agoraphobia.
* Participants with a diagnosis of ADHD will be included as long as their medication has been consistent for the past 6 months.
* Participants who are currently dependent on alcohol or other substances will be excluded, as this may negatively impact cognitive performance.
* Participants who currently are, or within the last 6 months, participating in a behavioral or pharmacological intervention will be excluded.

Contacts and Locations

Study Contact

Joseph DeGutis, Ph.D.

CONTACT

510-734-7705

degutis@wjh.harvard.edu

Principal Investigator

Joseph DeGutis, Ph.D.

PRINCIPAL_INVESTIGATOR

Harvard Medical School/VA Boston Healthcare Systems

Study Locations (Sites)

VA Boston Healthcare System

Boston, Massachusetts, 02130

United States

Collaborators and Investigators

Sponsor: Boston VA Research Institute, Inc.

Joseph DeGutis, Ph.D., PRINCIPAL_INVESTIGATOR, Harvard Medical School/VA Boston Healthcare Systems

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-10-15

Study Completion Date2025-02-21

Study Record Updates

Study Start Date2023-10-15

Study Completion Date2025-02-21

Terms related to this study

Additional Relevant MeSH Terms

Developmental Prosopagnosia