RECRUITING

Neurocognitive Abnormalities in Stimulant Abuse Among High-Risk Women

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Substance use disorders and psychopathy are serious and costly mental health issues. Psychopathy is known to be associated with aberrant moral decision making and there is considerable interest in determining whether substance use disorders lead to impairments in these same cognitive processes. Recent large-scale research initiatives in forensic settings have begun to identify substance abuse and psychopathy-related disruption in the neural mechanisms involved in moral decision-making processes, and associations between these neural networks and future relapse and antisocial behavior. Here the investigators extend prior work (with incarcerated men) to examine these issues among incarcerated women in order to better understand sex differences. This project addresses the overall lack of neurocognitive research in criminal offenders with substance use disorders, thereby focusing on a major public health issue in an underserved and understudied population.

Official Title

Neurocognitive Abnormalities in Stimulant Abuse Among High-Risk Women

Quick Facts

Study Start:2022-08-01
Study Completion:2027-05-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05845333

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 70 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Biological sex is female
  2. * Intelligence Quotient 70 or higher
  3. * Reading level 5th grade or higher
  4. * Able to speak and understand English
  1. * Uncorrectable auditory or visual deficits
  2. * Currently pregnant
  3. * MRI contraindication
  4. * Central nervous system disease
  5. * Current major medical condition
  6. * Hypertension with complications (e.g., stroke)
  7. * Diabetes with complications
  8. * Lifetime history of psychotic disorder
  9. * Self-report of psychotic disorder (with psychiatric hospitalization) in first degree relative
  10. * Drug use in past three months
  11. * History of arrest
  12. * Substance use beyond light alcohol or marijuana use
  13. * Currently taking psychotropic medications

Contacts and Locations

Study Contact

Carla Harenski
CONTACT
505-272-5028
charenski@mrn.org

Study Locations (Sites)

The Mind Research Network
Albuquerque, New Mexico, 87106
United States

Collaborators and Investigators

Sponsor: The Mind Research Network

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-08-01
Study Completion Date2027-05-31

Study Record Updates

Study Start Date2022-08-01
Study Completion Date2027-05-31

Terms related to this study

Additional Relevant MeSH Terms

  • Stimulant Abuse
  • Criminal Behavior