RECRUITING

Barriers and Facilitators of Parent-Child Communication in Children With Cancer Predisposition

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Testing children, adolescents, and young adults (CAYA) for a genetic risk for cancer can help with early prevention and detection of cancers through regular follow-ups and medical care. After receiving genetic test results, CAYA may not accurately understand what their results mean, and parents are often unsure about talking with their CAYA about their genetic risk for cancer. By understanding how parents communicate with their CAYA, the investigators can improve future genetic education to reduce cancer risk. Primary Objectives: * Identify qualities of parent-CAYA (child, adolescent, and young adults) communication about CAYAs' genomic cancer risk, and their association with CAYAs' psychosocial and prevention outcomes. * Examine the association between sociodemographic, cancer-related, and psychosocial factors and parent-CAYA communication regarding CAYAs' genomic risk for cancer. * Identify barriers and facilitators of parent-CAYA communication regarding CAYAs' genomic risk for cancer.

Official Title

Barriers and Facilitators of Parent-Child Communication in Children With Cancer Predisposition

Quick Facts

Study Start:2023-12-12

Study Completion:2028-10

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT05849155

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:10 Years to 24 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:No

Standard Ages:CHILD, ADULT

Inclusion Criteria	Exclusion Criteria
* Patient aged 10 to 24 years (inclusive) * Patient underwent germline genetic testing with a Pathogenic/Likely Pathogenic (P/LP) variant in a known cancer predisposition gene that increases risk for developing cancer * P/LP result disclosed to the patient * Patient has a primary caregiver willing to participate * Patient and participating caregiver able to speak and read English	* Patient is only a carrier of a recessive variant that does not alone increase risk for cancer * Inability or unwillingness of patient or participating caregiver or to give informed consent/assent * Participating caregiver is under the age of 18 years * Patient or participating caregiver has evidence of significant cognitive deficits (per medical record) that would interfere with the ability to comprehend study questions * Patient's medical status or condition precludes completion of study (as determined by medical team, patient, or parent)

Inclusion Criteria

Exclusion Criteria

* Patient aged 10 to 24 years (inclusive)
* Patient underwent germline genetic testing with a Pathogenic/Likely Pathogenic (P/LP) variant in a known cancer predisposition gene that increases risk for developing cancer
* P/LP result disclosed to the patient
* Patient has a primary caregiver willing to participate
* Patient and participating caregiver able to speak and read English

* Patient is only a carrier of a recessive variant that does not alone increase risk for cancer
* Inability or unwillingness of patient or participating caregiver or to give informed consent/assent
* Participating caregiver is under the age of 18 years
* Patient or participating caregiver has evidence of significant cognitive deficits (per medical record) that would interfere with the ability to comprehend study questions
* Patient's medical status or condition precludes completion of study (as determined by medical team, patient, or parent)

Contacts and Locations

Study Contact

Katianne Sharp, PhD

CONTACT

8662785833

referralinfo@stjude.org

Principal Investigator

Katianne Sharp, PhD

PRINCIPAL_INVESTIGATOR

St. Jude Children's Research Hospital

Study Locations (Sites)

St. Jude Children's Research Hospital

Memphis, Tennessee, 38105

United States

Collaborators and Investigators

Sponsor: St. Jude Children's Research Hospital

Katianne Sharp, PhD, PRINCIPAL_INVESTIGATOR, St. Jude Children's Research Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-12-12

Study Completion Date2028-10

Study Record Updates

Study Start Date2023-12-12

Study Completion Date2028-10

Terms related to this study

Additional Relevant MeSH Terms

Genetic Predisposition