RECRUITING

The Impact of Beef on Muscle Fatigue in Older Adults

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this controlled-feeding cross-over diet intervention is to compare a beef diet to a vegetarian diet on muscle fatigue in older adults. The aims are: AIM 1: To test the hypothesis that muscle fatigue is attenuated in older adults consuming beef compared to older adults consuming a plant-based diet. AIM2: To test the hypothesis that daily beef consumption improves biochemical indicators related to muscle fatigue. Participants will be randomized to consume either a beef-based diet or vegetarian diet under controlled-feeding conditions for 8 weeks. After a 2-week washout period, participants will cross-over to consume either the beef diet or vegetarian diet for 8 weeks. Body composition and functional muscle outcomes will be measured during each 8-week feeding period. Blood samples will also be collected.

Official Title

The Effect of Beta-Alanine and Carnosine From Beef Intake on Muscle Fatigue in Older Adults

Quick Facts

Study Start:2023-07-10
Study Completion:2024-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05860088

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:60 Years to 85 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Cydne A Perry, PhD
CONTACT
812 855 5087
cydperry@iu.edu

Principal Investigator

Cydne A Perry, PhD
PRINCIPAL_INVESTIGATOR
Indiana University, Bloomington

Study Locations (Sites)

Indiana University Bloomington
Bloomington, Indiana, 47405
United States

Collaborators and Investigators

Sponsor: Indiana University

  • Cydne A Perry, PhD, PRINCIPAL_INVESTIGATOR, Indiana University, Bloomington

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-07-10
Study Completion Date2024-12

Study Record Updates

Study Start Date2023-07-10
Study Completion Date2024-12

Terms related to this study

Keywords Provided by Researchers

  • Body Composition
  • Older Adults
  • Diet
  • Vegetarian
  • Meat
  • Beef
  • Controlled Feeding
  • Intervention

Additional Relevant MeSH Terms

  • Muscle Weakness
  • Muscle; Fatigue, Heart
  • Older Adults