RECRUITING

Breathing Training and Exercise Capacity in Non-CFB

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this research is to investigate whether a home-based and health coach supported specific breathing and respiratory muscle training program improves the ability to exercise, the function of the lungs and breathing muscles, and general clinical status in people with non-cystic fibrosis bronchiectasis (non-CFB).

Official Title

Home-based, Digitally Delivered Breathing Training in People With Non-cystic Fibrosis Bronchiectasis: A Randomized Control Trial

Quick Facts

Study Start:2024-01-15

Study Completion:2026-12-01

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT05860803

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:21 Years to 80 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:No

Standard Ages:ADULT, OLDER_ADULT

Inclusion Criteria	Exclusion Criteria
* Mayo Clinic patient with confirmed diagnosis of Non-Cystic Fibrosis Bronchiectasis (non-CFB): Non-CFB as confirmed by clinical history, including cough, shortness of breath, exertional dyspnea, pulmonary function tests, and high-resolution computed tomography. Patients will be considered clinically stable if there is no evidence of an exacerbation or change(s) in medical therapy in the previous three weeks. * Able and willing to provide informed consent to participate in the study.	* Presence of significant coexisting disease, neurological conditions, and/or orthopedic complications that affect ability to undertake exercise. * Presence of advanced heart failure. * Current use of antibiotics. * Acute exacerbation(s) within 3-weeks prior to study commencement. * Participation within a pulmonary rehabilitation program within 6-months prior to study commencement.

Inclusion Criteria

Exclusion Criteria

* Mayo Clinic patient with confirmed diagnosis of Non-Cystic Fibrosis Bronchiectasis (non-CFB): Non-CFB as confirmed by clinical history, including cough, shortness of breath, exertional dyspnea, pulmonary function tests, and high-resolution computed tomography. Patients will be considered clinically stable if there is no evidence of an exacerbation or change(s) in medical therapy in the previous three weeks.
* Able and willing to provide informed consent to participate in the study.

* Presence of significant coexisting disease, neurological conditions, and/or orthopedic complications that affect ability to undertake exercise.
* Presence of advanced heart failure.
* Current use of antibiotics.
* Acute exacerbation(s) within 3-weeks prior to study commencement.
* Participation within a pulmonary rehabilitation program within 6-months prior to study commencement.

Contacts and Locations

Principal Investigator

Bryan Taylor, PhD

PRINCIPAL_INVESTIGATOR

Mayo Clinic

Study Locations (Sites)

Mayo Clinic Florida

Jacksonville, Florida, 32224

United States

Collaborators and Investigators

Sponsor: Mayo Clinic

Bryan Taylor, PhD, PRINCIPAL_INVESTIGATOR, Mayo Clinic

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-01-15

Study Completion Date2026-12-01

Study Record Updates

Study Start Date2024-01-15

Study Completion Date2026-12-01

Terms related to this study

Additional Relevant MeSH Terms

Non-cystic Fibrosis Bronchiectasis