RECRUITING

Liposomal Bupivacaine and Transoral Robotic Surgery

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study is for patients with oropharyngeal squamous cell carcinoma. We want to learn more about how we can optimize pain control in patients who undergo transoral robotic surgery (TORS) for oropharyngeal squamous cell carcinoma. Our goal is to determine if a local anesthetic called EXPAREL® (Liposomal Bupivacaine) impacts postsurgical pain and swallow function in patients with oropharyngeal squamous cell carcinoma undergoing TORS. EXPAREL® is an FDA-approved anesthetic drug that provides long-lasting and precise pain relief when injected into the surgical wound. Our study team wants to determine if injecting EXPAREL® into the surgical wound will provide better pain relief and swallow function when compared to patients who do not undergo postoperative EXPAREL® injection. Both options for postoperative pain control are considered standard of care for patients undergoing TORS.

Official Title

Impact of Liposomal Bupivacaine on Post-operative Pain, Opioid Use, and Swallow Function in Transoral Robotic Surgery

Quick Facts

Study Start:2023-06-01
Study Completion:2026-01-15
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05862792

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Adult patients, greater than or equal to 18 years of age; Patients of all genders; Patients undergoing transoral robotic surgery; Patient who are able and willing to give consent
  1. * Patients with an allergy to Bupivacaine or other amide anesthetics; Patients with a carnitine deficiency

Contacts and Locations

Study Contact

Thorsen Haugen, MD
CONTACT
570-214-7866
thaugen@geisinger.edu

Study Locations (Sites)

Geisinger Medical Center
Danville, Pennsylvania, 17821
United States

Collaborators and Investigators

Sponsor: Geisinger Clinic

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-06-01
Study Completion Date2026-01-15

Study Record Updates

Study Start Date2023-06-01
Study Completion Date2026-01-15

Terms related to this study

Keywords Provided by Researchers

  • oropharyngeal cancer
  • squamous cell carcinoma
  • postoperative pain
  • transoral robotic surgery

Additional Relevant MeSH Terms

  • Oropharyngeal Cancer
  • Dysphagia, Oropharyngeal
  • Post Operative Pain
  • Transoral Robotic Surgery