RECRUITING

SCIVAX: Biomarkers of Immune Dysfunction and Vaccine Responsiveness in Chronic SCI

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this observational research study is to better understand immune responses to vaccines against viruses (influenza or SARS-CoV2). The goal is to determine any differences in immune responses to vaccines in uninjured people and in people living with spinal cord injuries, who are typically at increased risk of infections.

Official Title

Biomarkers of Immune Dysfunction and Vaccine Responsiveness in People With Chronic Traumatic Spinal Cord Injury

Quick Facts

Study Start:2023-03-31
Study Completion:2027-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05869968

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 89 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. * Stage III-IV pressure ulcers
  2. * Cancer, chemotherapy, neutropenia
  3. * Pregnancy or lactation
  4. * No known SCI
  5. * Autoimmune disease
  6. * Pre-existing neurological disease
  7. * History of dementia
  8. * Any other condition that would compromise their ability to provide informed consent
  9. * Any other condition that a study physician feels would preclude participation or be contraindicated

Contacts and Locations

Study Contact

Welmince Pello, MPH
CONTACT
516-562-1331
wpello@northwell.edu
Joy Cambe, MD, MPH
CONTACT
516-562-1331
jcambe@northwell.edu

Principal Investigator

Ona Bloom, PhD
PRINCIPAL_INVESTIGATOR
Feinstein Institute for Medical Research; Northwell Health

Study Locations (Sites)

Northwell Health
Manhasset, New York, 11030
United States

Collaborators and Investigators

Sponsor: Northwell Health

  • Ona Bloom, PhD, PRINCIPAL_INVESTIGATOR, Feinstein Institute for Medical Research; Northwell Health

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-03-31
Study Completion Date2027-12-31

Study Record Updates

Study Start Date2023-03-31
Study Completion Date2027-12-31

Terms related to this study

Keywords Provided by Researchers

  • Chronic Spinal Cord Injury
  • Flu Vaccination
  • COVID-19 Vaccination
  • Immune Responsiveness

Additional Relevant MeSH Terms

  • Spinal Cord Injuries
  • Traumatic Spinal Cord Injury
  • Healthy Controls
  • Flu Vaccine
  • COVID-19 Vaccine