ACTIVE_NOT_RECRUITING

Implementation of Collaborative Care for Depression in VA HIV Clinics

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

HIV Translating Initiatives for Depression into Effective Solutions (HITIDES) is a team-based service to manage depression in Veterans Living with HIV (VLWH). This service is more effective for managing depression than the care VLWH usually receive and saves resources. HITIDES is also liked by HIV care providers and VLWH. Despite this, no VA clinics currently offer this service. This study examines two approaches to engage clinics with HITIDES, the resulting effects on VLWH, and the costs of these approaches. The first approach includes recruiting an HIV care provider at the site to help connect with the service and a network of providers to support this person. The second approach uses an additional external expert to facilitate these connections. Understanding how to connect Veterans to the HITIDES service will allow VA to improve depression care for VLWH and save VA resources.

Official Title

Implementation of Collaborative Care for Depression in VA HIV Clinics: Translating Initiatives for Depression Into Effective Solutions (HITIDES)

Quick Facts

Study Start:2024-08-01
Study Completion:2027-07-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:ACTIVE_NOT_RECRUITING

Study ID

NCT05901272

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:Not specified
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * have an adequately sized (i.e. greater than 20) population of Veterans Living with HIV,
  2. * have adequate PHQ-2 screen data to assess depression prevalence,
  3. * can identify a clinical champion for implementation activities,
  4. * are willing to participate, and
  5. * allow for diversity and balance of clinic characteristics across arms (e.g. rate of referral to specialty mental health for VLWH and presence of HIV-only specialty clinic versus broad infectious disease clinic).
  6. * For criterion 5, these factors that are important will be determined with VISN 10 clinical leadership and the research advisory council. Randomization at the VAMC level has limited ability to completely balance observed and unobserved health-system factors. However, efforts to balance key site characteristics are important; therefore, site-level characteristics thought to impact implementation efforts were identified by building consensus among HIV, Hepatitis, and Related Conditions Program (HHRC) leadership and the HIV care and implementation experts on the research team. Data on the following observable site-level characteristics will be collected from these sites during Year 1 of the study: baseline PHQ-2 screen rate, clinic size (unique patients, provider full-time equivalents \[FTE\], change in enrollment over the past 3 years), and current care manager FTE. Based on the five criteria described above and the power calculation below, eight eligible sites will be selected. Sites will be grouped into four couplets based on balance of the identified site-level characteristics.
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Principal Investigator

Jacob T Painter, PhD PharmD
PRINCIPAL_INVESTIGATOR
Central Arkansas Veterans Healthcare System , Little Rock, AR
Eva N Woodward, PhD MA BS
PRINCIPAL_INVESTIGATOR
Central Arkansas Veterans Healthcare System , Little Rock, AR

Study Locations (Sites)

Central Arkansas Veterans Healthcare System , Little Rock, AR
Little Rock, Arkansas, 72205
United States

Collaborators and Investigators

Sponsor: VA Office of Research and Development

  • Jacob T Painter, PhD PharmD, PRINCIPAL_INVESTIGATOR, Central Arkansas Veterans Healthcare System , Little Rock, AR
  • Eva N Woodward, PhD MA BS, PRINCIPAL_INVESTIGATOR, Central Arkansas Veterans Healthcare System , Little Rock, AR

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-08-01
Study Completion Date2027-07-31

Study Record Updates

Study Start Date2024-08-01
Study Completion Date2027-07-31

Terms related to this study

Keywords Provided by Researchers

  • HIV
  • Depression
  • Hybrid type 3 effectiveness-implementation trial
  • Facilitation

Additional Relevant MeSH Terms

  • HIV
  • Depression