RECRUITING

A Clinical Registry of Spontaneous Intracranial Hypotension

Description

The purpose of this research is to determine the efficacy of paraspinal vein embolization for treatment of digital subtraction myelography (DSM) or CT myelography (CTM) confirmed cerebrospinal fluid (CSF)-venous fistulas so that researchers can inform the development and design of future clinical trials of this technique.

Conditions

Spontaneous Intracranial Hypotension
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Related Conditions:

Spontaneous Intracranial Hypotension

Study Overview

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Study Details

Study overview

The purpose of this research is to determine the efficacy of paraspinal vein embolization for treatment of digital subtraction myelography (DSM) or CT myelography (CTM) confirmed cerebrospinal fluid (CSF)-venous fistulas so that researchers can inform the development and design of future clinical trials of this technique.

Spontaneous Intracranial Hypotension Registry

A Clinical Registry of Spontaneous Intracranial Hypotension

Condition
Spontaneous Intracranial Hypotension
Intervention / Treatment

-

Contacts and Locations

Rochester

Mayo Clinic Minnesota, Rochester, Minnesota, United States, 55905

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Study subjects will be patients who meet the International Classification of Headache - Disorders 3rd Edition (ICHD-3) criteria for a diagnosis of SIH or the Schievink criteria with imaging confirmed CSF-venous fistulas on DSM or CTM.
  • * Availability of a clinically prescribed contrast enhanced MRI positive for SIH.
  • * Negative urine or serum pregnancy test at time of study consent and three-months.
  • * Patients who have a contraindication or inability to undergo the procedure (i.e., severe contrast allergy).
  • * Inability to provide informed consent.
  • * Expected inability to complete the follow-up assessment.
  • * Current pregnancy or breast-feeding during study enrollment (from consent to study conclusion approximately 90-days).

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Mayo Clinic,

Waleed Brinjikji, MD, PRINCIPAL_INVESTIGATOR, Mayo Clinic

Study Record Dates

2026-07