RECRUITING

Open Trial of Trauma-focused Psychodynamic Psychotherapy for People Living With HIV and PTSD

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

People living with HIV (PLWH) have a higher rate of post-traumatic stress disorder (PTSD) diagnosis than the general population. Comorbid PTSD is also associated with negative HIV-related health outcomes. Unfortunately, little outcome research has examined the usefulness of PTSD treatments for PTSD. This pilot study adapts for PLWH a non-exposure based psychotherapy for PTSD focused on reflecting on one's emotions and relationships and understanding and working through how trauma may have disrupted them. The study team is interested in better understanding the needs of PLWH with PTSD, learning whether PLWH with PTSD find this treatment acceptable and helpful, and beginning to understand the relationship between HIV-related health factors (e.g., inflammation and stress biology) and PTSD, and how these health factors may improve during treatment.

Official Title

Pilot Feasibility Proposal to Adapt Trauma-focused Psychodynamic Psychotherapy (TFPP) for PLWH and PTSD

Quick Facts

Study Start:2024-04-26
Study Completion:2025-04
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05929911

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Diagnosis of DSM-5 defined PTSD, per the Clinician Administered PTSD Scale \& CAPS-5 total severity score greater than or equal to 25
  2. * HIV diagnosis (by medical records or HIV testing)
  3. * Stable psychiatric/psychotropic medication for \>=2 months and ongoing during treatment
  1. * Psychosis
  2. * Bipolar I
  3. * Acute suicidality
  4. * Current substance use disorder
  5. * Organic mental syndrome or intellectual disability
  6. * Unstable non-HIV medical conditions

Contacts and Locations

Study Contact

John R Keefe, PhD
CONTACT
703-981-7184
john.keefe@einsteinmed.edu
Barbara L Milrod, MD
CONTACT
917-593-1377
bmilrod@montefiore.edu

Principal Investigator

Barbara Milrod, MD
PRINCIPAL_INVESTIGATOR
Montefiore Medical Center

Study Locations (Sites)

Albert Einstein College of Medicine
Bronx, New York, 10461
United States

Collaborators and Investigators

Sponsor: Montefiore Medical Center

  • Barbara Milrod, MD, PRINCIPAL_INVESTIGATOR, Montefiore Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-04-26
Study Completion Date2025-04

Study Record Updates

Study Start Date2024-04-26
Study Completion Date2025-04

Terms related to this study

Keywords Provided by Researchers

  • PTSD
  • HIV
  • psychotherapy
  • trauma

Additional Relevant MeSH Terms

  • Post Traumatic Stress Disorder
  • HIV