RECRUITING

Virtual Rehabilitation in HCT

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Chronic GVHD (cGVHD) is a major cause of illness in patients who undergo hematopoietic transplantation (HCT). GVHD can affect any organ in the body, can require several years of treatment, and can impact the quality of life (QoL). Physical activity and exercise have been shown to enhance fitness and improve QoL in chronic illnesses including GVHD, however, patients often have barriers to attending sessions including distance, risk of infection, and physical therapists' lack of experience with pediatric patients. The team's goal is to assess whether a virtual rehabilitation program in children post-HCT (including children with chronic GVHD) is feasible and whether its implementation will improve physical functioning and QoL. Patients between the ages of 8 and 23 years who are at least one hundred days post-HCT will be eligible for participation. Patients will have an assessment by a pediatric physical therapist at the time of study entry, at the end of the rehabilitation program, and approximately 3 months later. They will be supplied with some exercise equipment (such as dumbbells and resistance bands). Patients will have twice weekly half-hour one-on-one online sessions with the physical therapist for 12 weeks. Patients will be recruited through the bone marrow transplant clinic.

Official Title

A Pilot Study of Virtual Rehabilitation After Hematopoietic Cell Transplantation

Quick Facts

Study Start:2023-07-31
Study Completion:2027-08
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05943964

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:8 Years to 23 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT
Inclusion CriteriaExclusion Criteria
  1. * Recipients between the ages of 8 and 23 years ≥100 days post allogeneic HCT.
  2. * Patients 8-14 years old should have a caregiver willing to assist with the implementation of the exercises during the session
  3. * Patients should have access to devices and a reliable internet connection.
  4. * Patients should be cleared for exercise by their physician
  5. * Patients are eligible to participate regardless of underlying diagnosis, preparative regimen, or graft source.
  1. * Any physical impediment to exercise as evaluated by the treating physician.
  2. * Non-English-speaking patients (due to a lack of available interpreters through the telemedicine platform).

Contacts and Locations

Study Contact

Muna Qayed, MD, MsCR
CONTACT
(404) 785-1112
mqayed@emory.edu

Principal Investigator

Muna Qayed, MD, MsCR
PRINCIPAL_INVESTIGATOR
Emory University

Study Locations (Sites)

Children's Healthcare of Atlanta
Atlanta, Georgia, 30322
United States

Collaborators and Investigators

Sponsor: Emory University

  • Muna Qayed, MD, MsCR, PRINCIPAL_INVESTIGATOR, Emory University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-07-31
Study Completion Date2027-08

Study Record Updates

Study Start Date2023-07-31
Study Completion Date2027-08

Terms related to this study

Keywords Provided by Researchers

  • Virtual Rehabilitation
  • Virtual Exercise
  • Physical fitness

Additional Relevant MeSH Terms

  • Hematopoietic Cell Transplant