RECRUITING

Model-informed Patient-specific Rehabilitation Using Robotics and Neuromuscular Modeling

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Stroke is the third leading cause of death and the primary cause of long-term disability in the United States, affecting approximately 795,000 people each year. Hemiparesis, or unilateral weakness, is common after stroke and responsible for changes in muscle activation and movement patterns as well as declines in walking speed. It has been shown that increased walking speed directly corresponds to a higher quality of life in older adults and therefore, is often the goal of motor rehabilitation after stroke. However, there is no consensus on the best method for improving walking function after stroke and the results of post-stroke gait studies vary widely across sites and studies. Walking is one of the human's most important functions that serve survival, progress, and interaction. The force between the foot and the walking surface is very important. Although there have been many studies trying to understand this, there is a need for the development of a system that can advance research and provide new functionality. In this work, we will conduct a series of studies that attempt to analyze human gait and adaptations from different perspectives.

Official Title

Model-informed Patient-specific Rehabilitation Using Robotics and Neuromuscular Modeling

Quick Facts

Study Start:2022-09-21
Study Completion:2026-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06008743

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 80 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. * Any neurological conditions (applicable to Group A - healthy subjects) or other neurological conditions in addition to stroke (applicable to Group B - stroke survivors);
  2. * Inability to walk outside the home before the stroke (applicable to Group B - stroke survivors);
  3. * Coronary artery bypass graft in the past 3 months, myocardial infarction in the past 3 months, uncontrolled or untreated atrial fibrillation, severe or painful peripheral vascular disease, diagnosis of heart failure, or unstable or untreated angina;
  4. * Expressive aphasia
  5. * Reported musculoskeletal pain or conditions that limit walking (such as tendonitis, arthritis, osteoporosis, spinal stenosis, or any orthopedic surgery or fracture to the legs or spine in the last 6 months);
  6. * Inability to communicate with investigators (e.g., due to severe aphasia or other cognitive impairment);
  7. * Severe respiratory problems such as chronic obstructive pulmonary disease (COPD);
  8. * Unexplained dizziness;
  9. * Weight greater than 250 pounds (lbs).
  10. * Inability to ascend and descend 4 steps with handrails using another person's assistance (if desired)

Contacts and Locations

Study Locations (Sites)

University of Delaware
Newark, Delaware, 19716
United States

Collaborators and Investigators

Sponsor: University of Delaware

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-09-21
Study Completion Date2026-06-30

Study Record Updates

Study Start Date2022-09-21
Study Completion Date2026-06-30

Terms related to this study

Additional Relevant MeSH Terms

  • Stroke