Observational Study of THC Concentrations in Acute Cannabinoid Intoxication

Eligibility Criteria

• 1. Subject visits emergency department for acute cannabinoid intoxication as evidenced by the following criteria:
• 1. Recent cannabis use within the last 12 hours
• 2. Clinically significant physiological abnormalities associated with cannabis use or problematic behavioral or psychological changes (e.g., altered perception, impaired motor coordination, euphoria, anxiety, a sensation of slowed time, impaired judgment, social withdrawal) that developed during, or shortly after, cannabis use
• 2. Subject (and/or parent/LAR when required) has the ability to communicate with comprehension with the study personnel at the time of consent/assent and the gathering of data other than plasma samples.
• 3. Subject (and/or parent/LAR when required) is willing and able to provide informed consent/assent.
• 1. Anything that would place the individual at increased risk or preclude the individual's full compliance with or completion of the study.
• 2. Individuals under the age of 18 who do not have a parent or legal representative present during the time at the ED.
• 3. Patients presenting with signs or symptoms attributable to another medical condition or better explained by another mental disorder.
• 4. Patient presenting with cannabis hyperemesis syndrome (CHS) or cannabis withdrawal syndrome (CWS)
• 5. Patients who are brought in by law enforcement, i.e., cannabis intoxication associated with a vehicle accident (driving under the influence).