RECRUITING

AM vs PM Exercise Training

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The treatment of high blood pressure, or hypertension, is multifaceted and can include pharmacological therapies (i.e., medications) and lifestyle modifications such as physical activity. Chronotherapy, which describes timing of a treatment with the body's daily rhythms, has recently been used with hypertension medications and has been shown to be effective at lowering blood pressure and reducing the risk of cardiovascular disease events. Specifically, taking medications in the evening was shown to be more effective than morning medication routines. Little information is available about the effectiveness of chronotherapy combined with exercise (i.e., planned physical activity) interventions in older adults with hypertension. The purpose of this study is to examine how exercise training performed in the morning and early evening affects blood pressure and other measures of blood vessel health in postmenopausal females with hypertension.

Official Title

Effects of AM vs. PM Exercise Training on Blood Pressure and Vascular Health in Postmenopausal Females With Hypertension

Quick Facts

Study Start:2024-06-11
Study Completion:2027-07-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06042439

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:55 Years to 80 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Systolic BP equal to or greater than 130 mmHg without BP medication or greater than 120 mmHg with medication and diastolic blood pressure equal to and greater than 80 mmHg
  2. * 55-80 years old
  3. * Post-menopausal female
  4. * Able to walk without assistance
  1. * Habitually physically active defined as 150 minutes of moderate-intensity or 75 minutes of vigorous-intensity aerobic physical activity per week
  2. * Overt pulmonary disease/condition as follows: chronic bronchitis, chronic obstructive pulmonary disease, emphysema, or pulmonary hypertension
  3. * Cardiometabolic disease/condition as follows: diabetes, heart failure, peripheral arterial disease, stroke, coronary artery disease, renal disease, secondary hypertension, chronic venous insufficiency or deep vein thrombosis within last 6 months
  4. * Cancer within last 5 years
  5. * Body mass index \>39 kg/m2
  6. * Current smoking or vape
  7. * Evening shift work
  8. * uncontrolled thyroid disorder
  9. * 2 or more falls in the last year
  10. * Anemia within 3 months of enrollment
  11. * Parkinson's disease
  12. * Dementia
  13. * Unstable angina
  14. * Acute pulmonary embolus or infarction
  15. * Acute myocarditis or pericarditis
  16. * Acute aortic dissection

Contacts and Locations

Study Contact

Jill Slade, PhD
CONTACT
5178843351
jslade@msu.edu
Katharine Currie, PhD
CONTACT
517-432-4073
curriek4@msu.edu

Study Locations (Sites)

Michigan State University
East Lansing, Michigan, 48824
United States

Collaborators and Investigators

Sponsor: Michigan State University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-06-11
Study Completion Date2027-07-01

Study Record Updates

Study Start Date2024-06-11
Study Completion Date2027-07-01

Terms related to this study

Additional Relevant MeSH Terms

  • Hypertension