RECRUITING

Non-Invasive Ventilation Versus Neurally-Adjusted Ventilatory Assistance (NAVA) for the Treatment of Bronchiolitis

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This project aims to answer whether the use of a Neurally-Adjusted Ventilatory Assistance mode for non-invasive ventilation in pediatric patients with bronchiolitis results in improved comfort and reduced escalations in therapy (including intubation) when compared to using a standard mode of non-invasive ventilation. Neurally-Adjusted Ventilatory Assistance (NAVA) has been shown to result in greater synchrony then the standard mode of non-invasive ventilation. The study team hypothesizes that this improved synchrony can result in important clinical improvements when NAVA is used to treat children with bronchiolitis.

Official Title

Comparison of Conventional Non-Invasive Ventilation and Neurally-Adjusted Ventilatory Assistance (NAVA) Non-Invasive Ventilation for the Treatment of Bronchiolitis

Quick Facts

Study Start:2023-12-18
Study Completion:2025-07
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06053684

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:0 Years to 2 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD
Inclusion CriteriaExclusion Criteria
  1. * Patients under the age of two years old with a diagnosis of bronchiolitis presenting to the pediatric ICU
  1. * Patients unable to utilize a nasogastric tube
  2. * Patients with a diagnosis of chronic lung disease, cyanotic heart lesions, or congestive heart failure
  3. * Patients with hypotonia
  4. * Patients likely to require imminent intubation: \>0.60 Fraction of Inspired Oxygen (FiO2); Carbon Dioxide (CO2) \> 60, frequent apneas, clinician determines patient unlikely to tolerate non-invasive modality)
  5. * Patients with hemodynamic instability, defined as the need for vasoactive medication

Contacts and Locations

Study Contact

Jacqueline Weingarten, MD
CONTACT
2017459825
jweingar@montefiore.edu
Timothy Brandt, MD
CONTACT
7186197494
tbrandt@montefiore.org

Principal Investigator

Jacqueline Weingarten, MD
PRINCIPAL_INVESTIGATOR
Physician

Study Locations (Sites)

Children's Hospital at Montefiore
Bronx, New York, 10467
United States

Collaborators and Investigators

Sponsor: Montefiore Medical Center

  • Jacqueline Weingarten, MD, PRINCIPAL_INVESTIGATOR, Physician

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-12-18
Study Completion Date2025-07

Study Record Updates

Study Start Date2023-12-18
Study Completion Date2025-07

Terms related to this study

Additional Relevant MeSH Terms

  • Bronchiolitis