RECRUITING

Cannabis THC Potency, Metabolism, and Cognitive Impairment in Young Adults

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this interventional study is to determine the impact of high potency THC product use on cognitive function of young adults aged 21-25. The main question it aims to answer is: will cannabis users who switch to less potent THC products demonstrate improved cognitive function compared to baseline? Other questions this study aims to answer include: * Can researchers accurately assess THC consumption among frequent cannabis users? * Can researchers effectively incentivize cannabis users to use less potent THC products? * Do genetic variations in THC metabolism impact urinary THC excretion? * Do genetic variations in THC metabolism impact cognitive performance in cannabis users? * Are quantitative urinary THC values predictive of cognitive impairment? * How can researchers use research findings to inform harm reduction practices for people who use cannabis? Participants will submit blood and urine samples and be incentivized to use less potent THC products.

Official Title

Impacts of THC Potency of Cannabis Concentrates and THC Metabolism on Cognitive Impairment in Young Adults

Quick Facts

Study Start:2025-03-17
Study Completion:2025-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06077292

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:21 Years to 25 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Between the ages of 21-25
  2. * Resides in San Francisco
  3. * Self-report cannabis concentrate use as their primary method of cannabis use
  4. * Self-report using cannabis daily or almost daily (i.e., at least 6 out of 7 days during each of the last 4 weeks)
  5. * Self-report only purchasing cannabis from regulated retail stores in California.
  1. * Pregnant
  2. * Regularly uses other drugs (other than nicotine)

Contacts and Locations

Study Contact

Alison Giovanelli, PhD
CONTACT
415-476-4575
Alison.Giovanelli@ucsf.edu

Principal Investigator

Veronika Mesheriakova, MD
PRINCIPAL_INVESTIGATOR
University of California, San Francisco
Michael Sofis, PhD
PRINCIPAL_INVESTIGATOR
Cannabis Public Policy Consulting

Study Locations (Sites)

University of California San Francisco
San Francisco, California, 94143
United States

Collaborators and Investigators

Sponsor: University of California, San Francisco

  • Veronika Mesheriakova, MD, PRINCIPAL_INVESTIGATOR, University of California, San Francisco
  • Michael Sofis, PhD, PRINCIPAL_INVESTIGATOR, Cannabis Public Policy Consulting

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-03-17
Study Completion Date2025-06-30

Study Record Updates

Study Start Date2025-03-17
Study Completion Date2025-06-30

Terms related to this study

Keywords Provided by Researchers

  • Cannabis
  • Marijuana
  • High Potency THC
  • Dabs
  • Wax
  • Young Adult
  • Youth

Additional Relevant MeSH Terms

  • Cannabis Use
  • THC
  • Marijuana Use
  • Cognitive Impairment
  • THC Vaping