Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
Eligibility Criteria
- * Participant scheduled for open pancreaticoduodenectomy or distal pancreatectomy for any diagnosis
- * Participant ≥ 18 years of age
- * Ability to understand nature and individual consequences of clinical trial
- * Written informed consent from participant or legally authorized representative
- * For participants of childbearing potential, a negative pregnancy test and adequate contraception until 14 days after trial intervention
- * Participant needs to have an operative drain (any closed suction drain) after the procedure
- * Participants that do not require arterial reconstruction
- * Participants that require minor portal venous recounstructions including patch venoplasty
- * Patients with previous history of adverse reaction to contrast dye, ICG or components of the dye
- * Prior pancreatectomy
- * Known diagnosis of hepatic insufficiency, hepatitis, liver fibrosis or cirrhosis, or chronic pancreatitis
- * Because this study focuses on hypoperfusion, patients will be excluded if in postoperative day 3-5 had any of the following: persistent SBP \<90 mmHg unresponsive to 1L crystalloid, unexpected ICU transfer, blood transfusion of \>2 units intraoperatively or 1 postoperatively, vasopressor treatment or ACLS protocol initiation
- * Organ failure, anuria or NSQIP-identified complication will be reviewed by PI and attending surgeon and excluded
- * Patients that require arterial reconstruction as part of their procedures
Ages Eligible for Study
18 Years to
Sexes Eligible for Study
ALL
Accepts Healthy Volunteers
No