RECRUITING

Outcomes and Quality of Life Following Rectal Artery Embolization for Bleeding Internal Hemorrhoids

Description

This study will assess how effective and safe rectal artery embolization works to treat symptomatic bleeding predominant internal hemorrhoids.

Conditions

Internal Hemorrhoid
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Related Conditions:

Internal Hemorrhoid

Study Overview

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Study Details

Study overview

This study will assess how effective and safe rectal artery embolization works to treat symptomatic bleeding predominant internal hemorrhoids.

Hemorrhoidal Embolization Trial-1 (HEMBO-1)

Outcomes and Quality of Life Following Rectal Artery Embolization for Bleeding Internal Hemorrhoids

Condition
Internal Hemorrhoid
Intervention / Treatment

-

Contacts and Locations

Rochester

Mayo Clinic Minnesota, Rochester, Minnesota, United States, 55905

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Grade II or III hemorrhoidal disease as determined by a board-certified colorectal surgeon.
  • * Persistent or recurrent symptoms following hygiene and dietary measures or medication.
  • * Bleeding predominant ± pain symptoms.
  • * Undergoing planned rectal artery embolization (RAE) per standard clinical care.
  • * Male or female with age greater than 18 years, with the capacity and willingness to provide a written informed consent.
  • * Negative pregnancy test (if applicable).
  • * Prior hemorrhoid surgery.
  • * Grade IV hemorrhoidal disease.
  • * Acute hemorrhoid complications.
  • * Chronic anal or perianal fissures.
  • * History of colorectal surgery or pelvic radiation.
  • * Inflammatory bowel disease.
  • * Portal hypertension or mesenteric venous congestion/occlusion.
  • * Inferior mesenteric artery (IMA) or internal iliac artery (IIA) stenosis or occlusion.
  • * Contraindication to iodinated contrast.
  • * Pregnant and/or breast-feeding subjects. A negative pregnancy test within 48 hours of the procedure per clinical care.

Ages Eligible for Study

18 Years to 90 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Mayo Clinic,

Scott Thompson, MD, PhD, PRINCIPAL_INVESTIGATOR, Mayo Clinic, Vascular and Interventional Radiology

Scott R Kelley, MD, PRINCIPAL_INVESTIGATOR, Mayo Clinic, Colon and Rectal Surgery

Study Record Dates

2026-12