RECRUITING

Orbit Study: A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Intrathecally Administered ION356 in Participants With Pelizaeus Merzbacher Disease (PMD)

Description

The primary purpose of this study is to evaluate the safety and tolerability of ION356.

Study Overview

Study Details

Study overview

The primary purpose of this study is to evaluate the safety and tolerability of ION356.

A Phase 1b Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of Intrathecally Administered ION356 in Patients With Pelizaeus Merzbacher Disease

Orbit Study: A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Intrathecally Administered ION356 in Participants With Pelizaeus Merzbacher Disease (PMD)

Condition
Pelizaeus-Merzbacher Disease
Intervention / Treatment

-

Contacts and Locations

Atlanta

Ionis Investigative Site, Atlanta, Georgia, United States, 30342

Philadelphia

Ionis Investigative Site, Philadelphia, Pennsylvania, United States, 19104

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

    Ages Eligible for Study

    2 Years to 17 Years

    Sexes Eligible for Study

    MALE

    Accepts Healthy Volunteers

    No

    Collaborators and Investigators

    Ionis Pharmaceuticals, Inc.,

    Study Record Dates

    2028-06