RECRUITING

Caries Detection With Two Different Caries Detecting Devices

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The primary aim of this study will be to compare the effectiveness of the novel LumiCare™ rinse and with QLF in determining caries progression. The secondary aim is to compare the progression of carious lesions between patients who reported use of e-cigarettes/vapes and those who did not.

Official Title

A Pilot Clinical Trial Comparing the Efficacy of Caries Detection With a Novel Caries Detecting Rinse and Existing Diagnostic Tools

Quick Facts

Study Start:2025-04
Study Completion:2027-10
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06152081

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:21 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Patients of TUSDM Comprehensive Care Clinic
  2. * Adult patients over the age of 21
  3. * Extreme/High Caries Risk classification per TUSDM Caries Management by Risk Assessment (CAMBRA) form
  4. * Presence of 2 or more initial active primary carious lesions on a free coronal surface of any tooth by visual assessment, QLF, and LumiCare™
  5. * Presence of at least 1 cavitated lesion
  6. * Updated (no more than 6 months old) bite wing radiographs available.
  7. * Patients who responded either yes/no to use of e-cigarettes/vapes
  8. * 1 active caries, 1 inactive caries and 1 sound tooth surface.
  1. * Low or moderate caries risk classification per TUSDM CAMBRA form
  2. * No clinically detectable carious lesions on free coronal surfaces
  3. * No cavitated caries lesions
  4. * Carious teeth with caries lesions concomitant with extrinsic stains, fluorosis, or developmental defects.
  5. * Patients who responded yes to the use of conventional cigarettes or smokeless tobacco

Contacts and Locations

Study Contact

Karina Irusa, BDS,MS
CONTACT
6176362408
dentalresearchadministration@tufts.edu
Ann-Marie Billig
CONTACT
6176363931
dentalresearchadministration@tufts.edu

Principal Investigator

Karina Irusa, BDS, MS
PRINCIPAL_INVESTIGATOR
Tufts University School of Dental Medicine

Study Locations (Sites)

Tufts University School of Dental Medicine
Boston, Massachusetts, 02111
United States

Collaborators and Investigators

Sponsor: Tufts University

  • Karina Irusa, BDS, MS, PRINCIPAL_INVESTIGATOR, Tufts University School of Dental Medicine

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-04
Study Completion Date2027-10

Study Record Updates

Study Start Date2025-04
Study Completion Date2027-10

Terms related to this study

Additional Relevant MeSH Terms

  • Caries,Dental