RECRUITING

Effects of Processed Foods on Brain Reward Circuitry and Food Cue Learning

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Examine if ultra-processed (UP) foods are more effective in activating reward, attention, and memory brain regions and in promoting food cue learning than minimally-processed foods. Assess individual differences in neurobehavioral responses to UP foods.

Official Title

Effects of Processed Foods on Brain Reward Circuitry and Food Cue Learning

Quick Facts

Study Start:2024-10-04

Study Completion:2029-02-28

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT06165952

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:13 Years to 15 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:No

Standard Ages:CHILD

Inclusion Criteria	Exclusion Criteria
* female and male adolescents 13-15 years of age * age- and sex- adjusted zBMI scores between the 25th and 75th percentile * participant and their guardian must be able to read and speak English to gather valid consent	* current eating disorders or other major psychiatric disorders (e.g., depression, bipolar, schizophrenia, substance use disorder) * fMRI contra-indicators (e.g., metal implants, braces, claustrophobia, pregnancy) * serious medical problems (e.g., Type 2 diabetes, cancer) * history of food allergies or restrictive dietary requirements (e.g., lactose intolerance, vegan) * use of psychoactive drugs more than once weekly * medications that impact appetite or reward functioning (e.g., metformin, anti-psychotic medication, insulin)

Inclusion Criteria

Exclusion Criteria

* female and male adolescents 13-15 years of age
* age- and sex- adjusted zBMI scores between the 25th and 75th percentile
* participant and their guardian must be able to read and speak English to gather valid consent

* current eating disorders or other major psychiatric disorders (e.g., depression, bipolar, schizophrenia, substance use disorder)
* fMRI contra-indicators (e.g., metal implants, braces, claustrophobia, pregnancy)
* serious medical problems (e.g., Type 2 diabetes, cancer)
* history of food allergies or restrictive dietary requirements (e.g., lactose intolerance, vegan)
* use of psychoactive drugs more than once weekly
* medications that impact appetite or reward functioning (e.g., metformin, anti-psychotic medication, insulin)

Contacts and Locations

Study Contact

Eric Stice, PhD

CONTACT

541-222-0615

estice@stanford.edu

Teena Ambrose, BS

CONTACT

310-658-6193

tambrose@stanford.edu

Principal Investigator

Eric Stice, PhD

PRINCIPAL_INVESTIGATOR

Stanford University

Study Locations (Sites)

Stanford University

Stanford, California, 94305

United States

Collaborators and Investigators

Sponsor: Stanford University

Eric Stice, PhD, PRINCIPAL_INVESTIGATOR, Stanford University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-10-04

Study Completion Date2029-02-28

Study Record Updates

Study Start Date2024-10-04

Study Completion Date2029-02-28

Terms related to this study

Additional Relevant MeSH Terms

Ultra-processed Foods (UP)