RECRUITING

Daily Aspirin Treatment After Preeclampsia

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Women who develop preeclampsia during pregnancy are four times more likely to develop cardiovascular disease later in life, even if they are otherwise healthy. The reason why this occurs may be related to lasting blood vessel damage after the pregnancy but there are currently no specific treatment strategies to prevent this disease progression. This study addresses this public health issue by examining whether starting low dose aspirin therapy after pregnancy is an effective treatment for lasting blood vessel damage in order to inform better clinical management of cardiovascular disease risk in women who have had preeclampsia.

Official Title

Aspirin for the Treatment of Vascular Dysfunction After Preeclampsia

Quick Facts

Study Start:2023-11-01
Study Completion:2026-02
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06168461

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 50 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:No
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * had preeclampsia in the past 5 years,
  2. * 18 years or older
  1. * current daily aspirin use,
  2. * skin diseases,
  3. * current tobacco or nicotine use (including vaping),
  4. * diagnosed or suspected hepatic or metabolic disease including chronic kidney disease (CKD) defined as reduced eGFR \< 60 mL/min/1.73m2,
  5. * statin or other cholesterol-lowering medication,
  6. * current antihypertensive medication,
  7. * history of hypertension prior to pregnancy,
  8. * history of gestational diabetes,
  9. * currently pregnancy,
  10. * body mass index \<18.5 kg/m2,
  11. * allergy to materials used during the experiment.(e.g. latex),
  12. * known allergies to study drugs,
  13. * bleeding disorders, peptic ulcer disease, gastritis, GI bleeding and gastroesophageal reflux disease (GERD).

Contacts and Locations

Study Contact

Anna Reid-Stanhewicz, PHD
CONTACT
319-467-1732
anna-stanhewicz@uiowa.edu

Study Locations (Sites)

University of Iowa
Iowa City, Iowa, 52242
United States

Collaborators and Investigators

Sponsor: Anna Stanhewicz, PhD

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-11-01
Study Completion Date2026-02

Study Record Updates

Study Start Date2023-11-01
Study Completion Date2026-02

Terms related to this study

Keywords Provided by Researchers

  • preeclampsia

Additional Relevant MeSH Terms

  • Preeclampsia