RECRUITING

MMRC Horizon One Adaptive Platform Trial Evaluating Therapies in RRMM

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This trial is an adaptive platform trial. The structure of the protocol allows the trial to evolve over time. Multiple investigational arms will be included within the trial under a Master Protocol (MP). These investigational arms may be added as appendices at different times depending on whether they are trial-ready and whether accrual in the trial will support another arm. Accrual to an arm will terminate in accord with the arm's appendix to the Master Protocol. The purpose of this proposed structure is to support the recurrent research challenge of efficiently evaluating what is the best therapy for a particular patient.

Official Title

A Phase II Randomized Adaptive Platform Trial Evaluating Novel Therapies in Relapsed or Refractory Multiple Myeloma

Quick Facts

Study Start:2024-11-30
Study Completion:2030-07-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06171685

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 99 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * For inclusion in the trial, all the following inclusion criteria must be fulfilled, as no waivers will be permitted:
  1. * For inclusion in the trial, all the following inclusion criteria must be fulfilled, as no waivers will be permitted:

Contacts and Locations

Study Contact

Jessica Vandermark
CONTACT
(203) 354-7215
vandermarkj@themmrf.org
Mercedes Martillo
CONTACT
martillom@themmrf.org

Principal Investigator

Hearn J Cho, MD, PhD
PRINCIPAL_INVESTIGATOR
Multiple Myeloma Research Foundation

Study Locations (Sites)

City of Hope
Duarte, California, 91010
United States
Tennessee Oncology
Nashville, Tennessee, 37203
United States

Collaborators and Investigators

Sponsor: Multiple Myeloma Research Consortium

  • Hearn J Cho, MD, PhD, PRINCIPAL_INVESTIGATOR, Multiple Myeloma Research Foundation

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-11-30
Study Completion Date2030-07-31

Study Record Updates

Study Start Date2024-11-30
Study Completion Date2030-07-31

Terms related to this study

Additional Relevant MeSH Terms

  • Relapse Multiple Myeloma
  • Refractory Multiple Myeloma