RECRUITING

High Confusion: Cannabis & Driving

Description

This study is being done to assess the feasibility of administrating Δ9-THC and Δ8-THC isolates and simultaneously adopting several data harmonization measures to generate uniquely translatable data. This project aims to (1) evaluate the feasibility and acceptability of administering ∆9-THC and Δ8-THC isolates using standardized cannabis dosing units to quantify ∆9-THC and Δ8-THC pharmacokinetics; and (2) evaluate the feasibility and acceptability of adopting standardized impairment detection methods and driving performance definitions and measures on quantifying ∆9-THC and Δ8-THC driving impairment compared to a placebo.

Conditions

Impairment, CognitiveImpairment of AttentionImpairment, Psychomotor
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Related Conditions:

Impairment, CognitiveImpairment of AttentionImpairment, Psychomotor

Study Overview

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Study Details

Study overview

This study is being done to assess the feasibility of administrating Δ9-THC and Δ8-THC isolates and simultaneously adopting several data harmonization measures to generate uniquely translatable data. This project aims to (1) evaluate the feasibility and acceptability of administering ∆9-THC and Δ8-THC isolates using standardized cannabis dosing units to quantify ∆9-THC and Δ8-THC pharmacokinetics; and (2) evaluate the feasibility and acceptability of adopting standardized impairment detection methods and driving performance definitions and measures on quantifying ∆9-THC and Δ8-THC driving impairment compared to a placebo.

High Confusion: Evaluating Effects of Popular Cannabis Isolates on Driving Performance

High Confusion: Cannabis & Driving

Condition
Impairment, Cognitive
Intervention / Treatment

-

Contacts and Locations

Madison

University of Wisconsin, Madison, Wisconsin, United States, 53792

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * At least 18 years of age, no older than 49 years of age
  • * Recent cannabis use (within past two years)
  • * Good mental health as determined by self-reported responses to the Psychopathology Screener
  • * Absence of any major medical, cardiovascular, endocrine, and neurological condition as determined by self-reported responses to the Medical History Screener
  • * In possession of a valid drivers' license with at least two years of driving experience
  • * English-speaking (able to provide consent and complete questionnaires)
  • * Written Informed Consent
  • * Any serious prior adverse response to cannabis
  • * History of or current substance use disorder as determined by self-reported responses to the Internalizing, Externalizing, and Substance Use Disorder Screener
  • * Pregnancy or lactation (pregnancy test, if needed)
  • * Use of medications that may impact driving ability (e.g., mood stabilizers, sedatives)

Ages Eligible for Study

18 Years to 49 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Wisconsin, Madison,

Heather Barkholtz, PhD, PRINCIPAL_INVESTIGATOR, University of Wisconsin, Madison

Study Record Dates

2025-04