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InformationSeekingMesolimbicEngagementStudy1

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Study 1 will use a novel Game Show task, in which the investigators manipulate participant's agency to control their learning environment to specify unguided exploration.

Official Title

The Influence of Mesolimbic-hippocampal Interactions on Episodic Memory During Active Information Seeking

Quick Facts

Study Start:2023-10-25

Study Completion:2024-02-09

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:COMPLETED

Study ID

NCT06257446

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 45 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:Yes

Standard Ages:ADULT

Inclusion Criteria	Exclusion Criteria
* 20/40 far acuity (either corrected or uncorrected) * In good medical health	* History of head injury * History of illness with Central Nervous Systems implications * On Medications that Affect blood flow response and alertness * Consumption of smoking and/or coffee 30 minutes prior to laboratory testing * Placement of a device contraindicated for magnetic resonance imaging including cardia pacemaker, aneurysm clip, cochlear implants, pregnancy, intra-uterine device, shrapnel, metal fragments in the eyes, neurostimulators * Weight \> 250lbs * Claustrophobia

Inclusion Criteria

Exclusion Criteria

* 20/40 far acuity (either corrected or uncorrected)
* In good medical health

* History of head injury
* History of illness with Central Nervous Systems implications
* On Medications that Affect blood flow response and alertness
* Consumption of smoking and/or coffee 30 minutes prior to laboratory testing
* Placement of a device contraindicated for magnetic resonance imaging including cardia pacemaker, aneurysm clip, cochlear implants, pregnancy, intra-uterine device, shrapnel, metal fragments in the eyes, neurostimulators
* Weight \> 250lbs
* Claustrophobia

Contacts and Locations

Study Locations (Sites)

Temple University

Philadelphia, Pennsylvania, 19122

United States

Collaborators and Investigators

Sponsor: Temple University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-10-25

Study Completion Date2024-02-09

Study Record Updates

Study Start Date2023-10-25

Study Completion Date2024-02-09

Terms related to this study

Additional Relevant MeSH Terms

Motivation