RECRUITING

The STRENGTHEN Study

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study uses two different types of interventions including electrical brain stimulation delivered during sleep, and brief, daily meditation training. The investigators are trying to figure out whether these techniques, either alone or in combination with each other, can positively impact the brain networks that support our ability to think flexibly and to regulate our emotions. 48 participants will be enrolled into each of 2 phases and can expect to be on study for up to 9 months.

Official Title

Hybrid Interventions to Optimize Neural Plasticity and Enhance Well-being: Mental Exercise, and Transcranial Electrical Stimulation With Temporal Interference: The STRENGTHEN Study - Phase 1 and 2

Quick Facts

Study Start:2024-03-06
Study Completion:2026-02
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06267521

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 50 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Tricia Denman
CONTACT
608-890-2960
tdenman@wisc.edu
Isa Dolski
CONTACT
608-265-8107
idolski@wisc.edu

Principal Investigator

Richard Davidson, PhD
PRINCIPAL_INVESTIGATOR
University of Wisconsin, Madison
Giulio Tononi, MD, PhD
PRINCIPAL_INVESTIGATOR
University of Wisconsin, Madison

Study Locations (Sites)

Center for Healthy Minds
Madison, Wisconsin, 53703
United States

Collaborators and Investigators

Sponsor: University of Wisconsin, Madison

  • Richard Davidson, PhD, PRINCIPAL_INVESTIGATOR, University of Wisconsin, Madison
  • Giulio Tononi, MD, PhD, PRINCIPAL_INVESTIGATOR, University of Wisconsin, Madison

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-03-06
Study Completion Date2026-02

Study Record Updates

Study Start Date2024-03-06
Study Completion Date2026-02

Terms related to this study

Additional Relevant MeSH Terms

  • Cognitive Flexibility
  • Emotional Regulation