RECRUITING

BostonGene and Exigent Genomic INsight Study

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The BEGIN Study by BostonGene and Exigent Genomic INsight evaluates the efficacy of comprehensive molecular testing in advanced cancer patients. Using the BostonGene Tumor Portrait test, the study aims to identify actionable findings, assess feasibility, and determine patient enrollment in clinical trials. Four cohorts of 100 patients each will be studied over two years, focusing on treatment decisions and patient outcomes. This study seeks to demonstrate the clinical utility of genomic testing in guiding therapy for advanced cancer patients in community settings.

Official Title

BostonGene and Exigent Genomic INsight (BEGIN) Study: A Prospective Study of Comprehensive Molecular Testing in Advanced Cancer Patients in the Community Setting

Quick Facts

Study Start:2024-04-08
Study Completion:2028-01-08
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06272864

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Patients must have a confirmed malignancy of:
  2. * Life expectancy \> 3 months as per the treating physician
  3. * Willingness to provide informed consent
  4. * Living in the United States at time of enrollment
  5. * Agree to participate in genomic and molecular profiling
  1. * not meeting the inclusion criteria

Contacts and Locations

Study Contact

Jessica Brown, PhD
CONTACT
512-864-4314
jessica.brown@bostongene.com

Study Locations (Sites)

Northwest Medical Specialities
Puyallup, Washington, 98373
United States

Collaborators and Investigators

Sponsor: BostonGene

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-04-08
Study Completion Date2028-01-08

Study Record Updates

Study Start Date2024-04-08
Study Completion Date2028-01-08

Terms related to this study

Keywords Provided by Researchers

  • Comprehensive Molecular Testing
  • BostonGene Tumor Portrait Test
  • Molecularly Matched Therapy
  • DNA and RNA Targets

Additional Relevant MeSH Terms

  • Breast Cancer
  • Non-small Cell Lung Cancer
  • Melanoma
  • Sarcoma