RECRUITING

Defining Treatment Outcomes and Genetic Architecture in Idiopathic Toe Walking*

Description

To compare and contrast the clinical, gait and parent-reported outcomes following either non-operative (casting) or operative treatment for children with idiopathic toe walking (ITW) and determine whether there are specific genes associated with ITW.

Conditions

Idiopathic Toe Walking
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Related Conditions:

Idiopathic Toe Walking

Study Overview

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Study Details

Study overview

To compare and contrast the clinical, gait and parent-reported outcomes following either non-operative (casting) or operative treatment for children with idiopathic toe walking (ITW) and determine whether there are specific genes associated with ITW.

Defining Treatment Outcomes and Genetic Architecture in Idiopathic Toe Walking*

Defining Treatment Outcomes and Genetic Architecture in Idiopathic Toe Walking*

Condition
Idiopathic Toe Walking
Intervention / Treatment

-

Contacts and Locations

Sacramento

Shriners Hospitals for Children, Sacramento, California, United States, 95817

Chicago

Shriners Hospitals for Children, Chicago, Illinois, United States, 60707

Lexington

Shriners Hospitals for Children, Lexington, Kentucky, United States, 40508

Portland

Shriners Hospitals for Children, Portland, Oregon, United States, 97239

Philadelphia

Shriners Hospitals for Children, Philadelphia, Pennsylvania, United States, 19140

Greenville

Shriners Hospitals for Children, Greenville, South Carolina, United States, 29605

Salt Lake City

Shriners Hospitals for Children, Salt Lake City, Utah, United States, 84103

Spokane

Shriners Children's Spokane, Spokane, Washington, United States, 99204

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Diagnosis of Idiopathic Toe Walking Persistent (ITWp)
  • 2. Between the ages of 6-18 years
  • 3. Passive dorsiflexion dorsiflexion with knee extension between -10 plantar flexion - + 5 degrees of dorsiflexion, DiGiovanni defined an isolated gastrocnemius contracture as maximum passive ankle dorsiflexion as \< 5 degrees with the knee in full extension
  • 1. Diagnosis of Autism or autism spectrum disorder
  • 2. Presence of any indicators of trauma, neuromuscular influence or neurogenic influence as identified by using the Toe Walking Tool

Ages Eligible for Study

6 Years to 18 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Shriners Hospitals for Children,

Jeremy Bauer, MD, PRINCIPAL_INVESTIGATOR, Shriners Hospitals for Children-Portland

Study Record Dates

2025-12-31