RECRUITING

Retinal Vascular Changes During Pregnancy

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this study is to better understand how the back part of the eye-called the retina and the choroid-changes during pregnancy. Specialized photos of the eye will be taken at three different timepoints: early in pregnancy (first or second trimester), late in pregnancy (third trimester), and after delivery. This imaging is non-invasive and does not require contact with the surface of the eye. The photos taken will allow assessment of specific parameters, like blood flow and the health of specialized cells that support vision. Understanding how the eyes change during pregnancy may help guide how retina specialists understanding of retinal disease during pregnancy and better inform pregnancy outcomes.

Official Title

Understanding Retinal Vascular Changes During Pregnancy and the Impact on Maternal and Fetal Health

Quick Facts

Study Start:2024-02-01
Study Completion:2027-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06311617

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:Not specified
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Patient age 18 years and older
  2. 2. Patient able to provide informed consent
  3. 3. Pregnant at time of enrollment and in the 1st or 2nd trimester of pregnancy
  1. 1. Other ocular disease that prevents imaging (significant cataract or other media opacity)
  2. 2. Unable to comply with imaging or follow-up through duration of study

Contacts and Locations

Study Contact

Marybeth Carter
CONTACT
615-936-2020
marybeth.l.carter@vumc.org
Elise Timtim, MD
CONTACT
615-936-2020
elise.timtim@vumc.org

Principal Investigator

Avni P Finn, MD, MBA
PRINCIPAL_INVESTIGATOR
Vanderbilt Eye Institute

Study Locations (Sites)

Vanderbilt University Medical Center
Nashville, Tennessee, 37232
United States

Collaborators and Investigators

Sponsor: Vanderbilt University Medical Center

  • Avni P Finn, MD, MBA, PRINCIPAL_INVESTIGATOR, Vanderbilt Eye Institute

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-02-01
Study Completion Date2027-01

Study Record Updates

Study Start Date2024-02-01
Study Completion Date2027-01

Terms related to this study

Keywords Provided by Researchers

  • Optical coherence tomography
  • Pregnancy
  • Imaging
  • Retina
  • Vascular
  • Fundus Photography

Additional Relevant MeSH Terms

  • Pregnancy