RECRUITING

Modulating Reward Learning Using Transcranial Magnetic Stimulation

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Our specific aim is to examine the effects of TMS on reward processing during goal-directed behavior. In these experiments the investigators will utilize a scalp-recorded brain oscillation called frontal midline theta that is believed to index the sensitivity of the cingulate cortex to reward feedback. Here the investigators will asked whether this electrophysiological signal can be modulated up or down using TMS while participants engage in decision making tasks, and if so, whether it would affect the encoding of rewards and subsequent choices during task performance.

Official Title

Modulating Reward Learning Using Transcranial Magnetic Stimulation

Quick Facts

Study Start:2024-02-14
Study Completion:2025-04-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06323057

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 55 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Be between the ages of 18 and 55 years old.
  2. * Be in stable mental and physical health.
  3. * If female, test non-pregnant.
  4. * Be willing to provide informed consent.
  5. * Be able to comply with protocol requirements and likely to complete all study procedures.
  1. * Contraindication to rTMS (history of neurological disorder or seizure, increased intracranial pressure, brain surgery, or head trauma with loss of consciousness for \> 15 minutes, implanted electronic device, metal in the head, or pregnancy).
  2. * History of autoimmune, endocrine, viral, or vascular disorder affecting the brain.
  3. * Life time history of mental disorders such as: Bipolar Affective disorder (BPAD), Schizophrenia, Post-traumatic Stress disorder (PTSD) or Dementia or Major Depression.
  4. * uninterruptable central nervous system medication

Contacts and Locations

Study Locations (Sites)

Rutgers University - Newark
Newark, New Jersey, 07102
United States

Collaborators and Investigators

Sponsor: Rutgers, The State University of New Jersey

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-02-14
Study Completion Date2025-04-30

Study Record Updates

Study Start Date2024-02-14
Study Completion Date2025-04-30

Terms related to this study

Keywords Provided by Researchers

  • transcranial magnetic stimulation
  • reward processing
  • EEG
  • theta

Additional Relevant MeSH Terms

  • Behavior