RECRUITING

Delirium Identification in Older Patients With Alzheimer's and Other Related Dementias In the Emergency Department

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Delirium is highly prevalent and very bad for patients with dementia. Delirium is a dangerous medical condition that occurs in 6-38% of older Emergency Department patients and 70% of ICU patients. A person who develops delirium in the ED or hospital has a 12 times higher odds of being newly diagnosed with dementia in the next year compared to a similar patient who does not become delirious. Delirium is especially dangerous for persons living with Alzheimer Disease and Related Dementias (AD/ADRD). Persons living with ADRD have an almost 50% chance of developing delirium in the hospital. Clinicians are bad at recognizing delirium. A recent systematic review led by the Geriatric Emergency Care Applied Research network (NIH funded) found that current delirium screening tools are at most 64% sensitive, meaning that physicians can identify some phenotypes of delirium well, but cannot easily rule out delirium in acutely ill older patients. The investigators propose integrating wrist biosensors into the emergency management of older adults with dementia. The investigators will monitor heart rate variability, movement, and electrodermal activity (electrical activity of at the level of the skin) to determine if an array of biosensors more sensitive to delirium than current verbal screening tools.

Official Title

Delirium Identification in Older Patients With Alzheimer's and Other Related Dementias In the Emergency Department Using Wrist Accelerometer Biosensors and Machine Learning

Quick Facts

Study Start:2024-04-10
Study Completion:2025-03-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06326424

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Not specified
Standard Ages:OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * adults patients 65+ years old with a known diagnosis of dementia or medical team highly suspects or confirms dementia this visit.
  2. * Emergency Department visit and/or hospitalization anticipated to last \>4 more hours from the time of enrollment.
  1. * Intubation/mechanical ventilation
  2. * Patients undergoing a procedure requiring sedation
  3. * Patients who cannot consent due to cognitive impairment and do not have a legally authorized representative or caregiver present.

Contacts and Locations

Study Contact

Lauren Southerland, MD MPH
CONTACT
614-366-8375
lauren.southerland@osumc.edu
Michael Hill, RN
CONTACT
michael.hill@osumc.edu

Principal Investigator

Edward Boyer, MD
STUDY_DIRECTOR
Ohio State University

Study Locations (Sites)

The Ohio State University Wexner Medical Center
Columbus, Ohio, 43210
United States

Collaborators and Investigators

Sponsor: Ohio State University

  • Edward Boyer, MD, STUDY_DIRECTOR, Ohio State University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-04-10
Study Completion Date2025-03-01

Study Record Updates

Study Start Date2024-04-10
Study Completion Date2025-03-01

Terms related to this study

Keywords Provided by Researchers

  • emergency department
  • delirium
  • older adults
  • dementia

Additional Relevant MeSH Terms

  • Delirium
  • Dementia
  • Hospital Acquired Condition