RECRUITING

Acceptability and Feasibility of Transcranial Magnetic Stimulation (TMS) for Depression in Multiple Sclerosis

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this single-arm, observational pilot study is to learn about the safety, feasibility, preliminary efficacy of TMS for the treatment of depression in people with MS. Participants will receive outpatient TMS treatment over the course of 5-6 weeks. Participants will complete validated questionnaires and exams before, during, and after treatment.

Official Title

Acceptability and Feasibility of Transcranial Magnetic Stimulation (TMS) for Depression in Multiple Sclerosis

Quick Facts

Study Start:2024-01-16
Study Completion:2026-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06329414

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 75 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Established diagnosis of multiple sclerosis (any subtype) by 2017 McDonald criteria
  2. * Established diagnosis of major depressive disorder (MDD) by DSM-5 criteria
  3. * Eligible for transcranial magnetic stimulation (rTMS) for depression
  1. * MS relapse and/or steroid use within 3 months
  2. * Active suicidal ideation
  3. * History of seizure/epilepsy, brain tumor, or stroke
  4. * History of bipolar disorder or psychosis
  5. * Currently or planning to become pregnant

Contacts and Locations

Study Contact

Kathleen Shangraw, MD
CONTACT
8015832500
kathleen.shangraw@hsc.utah.edu
Trieste Francis
CONTACT
trieste.francis@hsc.utah.edu

Study Locations (Sites)

University of Utah Health
Salt Lake City, Utah, 84108
United States

Collaborators and Investigators

Sponsor: University of Utah

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-01-16
Study Completion Date2026-01

Study Record Updates

Study Start Date2024-01-16
Study Completion Date2026-01

Terms related to this study

Keywords Provided by Researchers

  • multiple sclerosis
  • depression
  • major depressive disorder
  • treatment resistant depression
  • transcranial magnetic stimulation
  • TMS

Additional Relevant MeSH Terms

  • Multiple Sclerosis
  • Major Depressive Disorder
  • Treatment Resistant Depression