RECRUITING

A Study of AMG 732 in Healthy Participants and Participants With Thyroid Eye Disease

Description

The primary objective of Part A of this study is to investigate the safety and tolerability of AMG 732 after single subcutaneous (SC) doses. The primary objective of Part B of this study is to investigate the efficacy of AMG 732 in participants with Thyroid Eye Disease (TED) after multiple SC doses.

Study Overview

Study Details

Study overview

The primary objective of Part A of this study is to investigate the safety and tolerability of AMG 732 after single subcutaneous (SC) doses. The primary objective of Part B of this study is to investigate the efficacy of AMG 732 in participants with Thyroid Eye Disease (TED) after multiple SC doses.

A Phase 1/2, Randomized, Double-Masked, Placebo-Controlled, Multicenter Study to Assess the Safety, Pharmacokinetics, and Efficacy of AMG 732 in Healthy Subjects and Subjects With Moderate-to-Severe Active Thyroid Eye Disease

A Study of AMG 732 in Healthy Participants and Participants With Thyroid Eye Disease

Condition
Thyroid Eye Disease
Intervention / Treatment

-

Contacts and Locations

Jacksonville

Levenson Eye Associates, Jacksonville, Florida, United States, 32204

Kissimmee

Ilumina Medical Research, Kissimmee, Florida, United States, 34744

Las Vegas

Ppd Las Vegas Research Unit, Las Vegas, Nevada, United States, 89113

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

    Ages Eligible for Study

    18 Years to 65 Years

    Sexes Eligible for Study

    ALL

    Accepts Healthy Volunteers

    Yes

    Collaborators and Investigators

    Amgen,

    MD, STUDY_DIRECTOR, Amgen

    Study Record Dates

    2027-08-13