RECRUITING

Facilitating Neuroplastic Changes of Acute Stroke Survivors

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Conditions

StrokeParaplegiaAcute

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This project will develop a wearable rehabilitation robot suitable for in-bed acute stage rehabilitation. It involves robot-guided motor relearning, passive and active motor-sensory rehabilitation early in the acute stage post-stroke including patients who are paralyzed with no motor output. The early acute stroke rehabilitation device will be evaluated in this clinical trial.

Official Title

Facilitating Neuroplastic Changes of Acute Stroke Survivors With Severe Hemiplegia

Quick Facts

Study Start:2025-06-01
Study Completion:2028-08-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06404268

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:30 Years to 85 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Acute first time unilateral hemispheric stroke (hemorrhagic or ischemic stroke, 24 hours after admission to 1 month post-stroke at the start of the proposed treatment)
  2. * Hemiplegia or hemiparesis
  3. * 0≤Manual Muscle Testing (MMT)\<=2
  4. * Age 30-85
  5. * Ankle impairments including stiff calf muscles and/or inadequate dorsiflexion
  1. * Medically not stable
  2. * Associated acute medical illness that interferes with ability to training and exercise
  3. * No impairment or very mild ankle impairment of ankle
  4. * Severe cardiovascular problems that interfere with ability to perform moderate movement exercises
  5. * Cognitive impairment or aphasia with inability to follow instructions
  6. * Severe pain in legs
  7. * Severe ankle contracture greater than 15° plantar flexion (when pushing ankle to dorsiflexion)
  8. * Pressure ulcer, recent surgical incision or active skin disease with open wounds present below knee

Contacts and Locations

Study Contact

Soh-Hyun Hur
CONTACT
410 706-8625
SoHur@som.umaryland.edu

Principal Investigator

Li-Qun Zhang
PRINCIPAL_INVESTIGATOR
University of Maryland

Study Locations (Sites)

University of Maryland Baltimore
Baltimore, Maryland, 21201
United States
UMROI
Baltimore, Maryland, 21207
United States

Collaborators and Investigators

Sponsor: University of Maryland, Baltimore

  • Li-Qun Zhang, PRINCIPAL_INVESTIGATOR, University of Maryland

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-06-01
Study Completion Date2028-08-31

Study Record Updates

Study Start Date2025-06-01
Study Completion Date2028-08-31

Terms related to this study

Keywords Provided by Researchers

  • Stroke
  • Paraplegia
  • Acute

Additional Relevant MeSH Terms

  • Stroke