RECRUITING

MitoQ Treatment of Claudication: Myofiber and Micro-vessel Pathology

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

In our research, we are delving into whether taking MitoQ for six months can improve the symptoms and function of people diagnosed with peripheral artery disease, especially those who suffer from leg pain while walking, known as intermittent claudication. We will be checking if MitoQ helps people with claudication walk better, be more active every day, feel better about their lives, and if it enhances the health of their leg muscles.

Official Title

MitoQ Treatment of Claudication: Myofiber and Micro-vessel Pathology

Quick Facts

Study Start:2023-06-01
Study Completion:2027-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06409949

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:21 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. a positive history of chronic claudication
  2. 2. exercise-limiting claudication established by history and direct observation during a screening walking test administered by the evaluating vascular surgeon
  3. 3. documented lower extremity arterial occlusive disease based on ankle/brachial index measurements and/or arterial imaging
  4. 4. stable blood pressure, lipid and diabetes regimens and risk factor control for 6 weeks.
  1. 1. rest pain or tissue loss due to PAD (Fontaine stage III and IV)
  2. 2. acute lower extremity ischemic event
  3. 3. walking capacity significantly and primarily limited by conditions other than claudication including leg (joint/musculoskeletal, neurologic) and systemic (heart, lung disease) pathology.

Contacts and Locations

Study Contact

Holly DeSpiegelaere, BSN RN CCRC
CONTACT
402-995-4171
Holly.DeSpiegelaere@va.gov

Principal Investigator

Iraklis Pipinos, MD
PRINCIPAL_INVESTIGATOR
University of Nebraska

Study Locations (Sites)

VA Medical Center
Omaha, Nebraska, 68105
United States

Collaborators and Investigators

Sponsor: University of Nebraska

  • Iraklis Pipinos, MD, PRINCIPAL_INVESTIGATOR, University of Nebraska

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-06-01
Study Completion Date2027-06

Study Record Updates

Study Start Date2023-06-01
Study Completion Date2027-06

Terms related to this study

Additional Relevant MeSH Terms

  • Peripheral Arterial Disease