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The Prevalence of Neuropathic Pain Pathophysiology Associated With Ankle Fracture

Description

This application addresses the Peer Reviewed Medical Research Program Investigator-Initiated Research Award FY21 W81XWH-22-CPMRP-IIRA area of Chronic Pain Management Research Program- The investigators will utilize subjects who have sustained ankle fractures and may develop chronic pain following bone union. No attempt will be made to affect the experimental outcome in the subjects. This study will adhere to a core set of standards for rigorous study design and reporting to maximize the reproducibility and translational potential of research.

Study Overview

Study Details

Study overview

This application addresses the Peer Reviewed Medical Research Program Investigator-Initiated Research Award FY21 W81XWH-22-CPMRP-IIRA area of Chronic Pain Management Research Program- The investigators will utilize subjects who have sustained ankle fractures and may develop chronic pain following bone union. No attempt will be made to affect the experimental outcome in the subjects. This study will adhere to a core set of standards for rigorous study design and reporting to maximize the reproducibility and translational potential of research.

The Prevalence of Neuropathic Pain Pathophysiology Associated With Ankle Fracture

The Prevalence of Neuropathic Pain Pathophysiology Associated With Ankle Fracture

Condition
Neuropathic Pain
Intervention / Treatment

-

Contacts and Locations

Indianapolis

Indiana University School of Medicine, Indianapolis, Indiana, United States, 46202

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * 1) 18-85 years old
  • * 2) an isolated rotational ankle (AO/OTA 44 types A-C) fracture that is treated operatively
  • * 3) Abbreviated Injury Scale \< 3 for non-extremity body systems
  • * 4) can speak, read, and understand English
  • * 1) treated for a chronic pain condition prior to their qualifying injury
  • * 2) on a pain contract
  • * 3) multiple fractures
  • * 4) pathologic fracture
  • * 5) develops a complication in post-operative period or undergoes secondary procedures for the fracture

Ages Eligible for Study

18 Years to 85 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Indiana University,

Study Record Dates

2027-12-31